Vaccines Flashcards

1
Q

** The GOAL of VACCINATION is to attempt to STIMULATE _________ immune system to create _________

A

adaptive

memory

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2
Q

** An _________ is a substance than ENHANCES antigen specific immune response

A

Adjuvant

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3
Q

** ADJUVANTS increase _________

A

immune response

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4
Q

** Aluminum adjuvant STIMULATES the production of _________

A

cytokines

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5
Q

Excessive use of ANTACIDS is a common cause of _________ toxicity, especially in those with kidney problems

A

aluminum (toxicity)

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6
Q

Aluminum _________ is considered SAFER than aluminum _________

A

phosphate

hydroxide

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7
Q

Protection provided to all individuals in a population due to the inability of a pathogen to effectively spread when a larger proportion of individuals are resistant is known as _________

A

herd immunity

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8
Q

In MEMORY T and B cells, Dendritic cells use _________ molecules to present peptides derived from the invaders proteins

A

MHC II

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9
Q

_________ B and T cells can be produced efficiently, even when NO immune system cells have been INFECTED by the attacker

A

MEMORY B and T cells

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10
Q

** MEMORY KILLER T (CTLs) cells can be produced during a microbial attack

true/false

A

true

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11
Q

** In MEMORY KILLER T (CTLs) cells, the INFECTED microbe must be presented to the APC on a _________ molecule

A

MHC I

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12
Q

** MEMORY HELPER T and B cells can be produced even when the invader DOES NOT infect the APC

true/false

A

true

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13
Q

** In _________ cells, the attacker MUST infect the APC

A

MEMORY KILLER T cells (CTLs)

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14
Q

VIRUS-SPECIFIC CTLs can be generated even when the virus DOES NOT infect the APCs, this is known as _________

A

cross presentation

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15
Q

** _________ vaccines are designed NOT to INFECT the recipient of the vaccine

A

KILL Vaccines/NON-Infectious Vaccines

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16
Q

The SALK vaccine and COMMON FLU vaccine are examples of _________ vaccines

A

KILL/NON-INFECTIOUS vaccines

17
Q

_________ vaccines are used to treat BACTERIAL infection

A

toxoid

18
Q

TOXOID vaccines require MULTIPLE DOESES during child and must be re-administered every _________ years

A

10

19
Q

When a TOXOID vaccine is injected, it mobilizes _________

A

B cells

20
Q

DIPTHERIA and TETANUS vaccines are examples of _________ vaccines

A

TOXOID vaccines

21
Q

An example of a NON-Infectious (KILL) Vaccine prepares using ONLY certain parts of a pathogen is a _________ vaccine

A

Acellular

22
Q

Pertussis vaccine is an example of a _________ vaccine (2 parts)

A

Acellular (vaccine)

(KILL-NON infectious) vaccine

23
Q

Which of the vaccines is the vaccine of CHOICE?

A

Acellular vaccine

24
Q

** NON-Infectious (KILL) vaccines DO NOT produce _________ cells

A

Memory KILLER T cells (CTLs) (Bc the APC is NOT INFECTED)

They DO produce Memory HELPER T and B cells

25
Q

** Growing a virus in a laboratory in a cell type which is NOT normal to the host is an example of a _________ vaccine

A

Attenuated (LIVE) vaccine

26
Q

** In _________ vaccines, the virus will accumulate MUTATIONS, which WEAKEN the virus

A

Attenuated/LIVE (vaccines)

27
Q

** _________ vaccines CAN produce Memory KILLER T (CTLs) Cells

A

Attenuated (LIVE) vaccines

28
Q

** When a person is vaccinated with an ATTENUATED (LIVE) Vaccine, they can INFECT OTHER PEOPLE who come into contact with them. This is known as _________

A

contact immunity

Spreads immunity around

29
Q

** Contact immunity is associated with _________ vaccines

A

Attenuated (LIVE) vaccines

30
Q

People with a WEAK immune system may NOT be suitable for a _________ vaccine

A

Attenuated/LIVE (vaccine)

31
Q

A _________ vaccine uses GENETIC ENGINEERING to introduce a SINGLE gene from a pathogenic microbe into a virus that DOESN’T cause DISEASE

A

carrier (vaccine)

32
Q

The process of using a CARRIER vaccine can be referred to as a _________

A

trojan horse

33
Q

Vaccination with a CARRIER vaccine should generate _________ cells to help protect against future attack

A

Memory KILLER T (CTLs) cells

34
Q

There is NO CHANCE that a _________ vaccine will cause the disease that it is intended to protect against

A

carrier vaccine

35
Q

** Organisms are created and genes are removed that impair virulence and/or replication describes _________ vaccines

A

recombinant vaccines

36
Q

HPV and Hepatitis B vaccines are examples of _________ vaccines

A

RECOMBINANT Vaccines

37
Q

** NON-Infectious (KILL) vaccines DO produce _________ cells

A

memory HELPER B and T cells