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Pharmacology - Katzung > 34 - Coagulation - Anticoagulants - Heparin - Chemistry > Flashcards

34 - Coagulation - Anticoagulants - Heparin - Chemistry Flashcards

1
Q

داروهایی ک بحث میشه؟

3 مورد

A

1) Heparin
2) LMWH
3) Fondaparinux

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2
Q

هپارین

چ نوع مولکولی؟

A

large sulfated polysaccharide polymer
بزرگ
سولفاته
پلی‌مر پلی‌ساکاریدی

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3
Q

منبع هپارین چیه؟

A

animal source

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4
Q

هپارین
وزن مولکولی میانگین؟
(هر کدوم از مولکول‌های هپارین وزن متفاوتی دارن)

A

15,000 - 20,000

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5
Q

ویژگی مولکول هپارین؟

اسیدی/قلیایی

A

اسیدی شدید

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6
Q

هپارین
گفتیم که اسیدیه
چ چیزی میتونه خنثی کنه؟

A

ماده بازی

Protamine

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7
Q

هپارین

نحوه تجویز؟

A

IV

SubQ

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8
Q

IM
داریم؟
چرا؟

A

ممنوع

تشکیل هماتوم

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9
Q

LMWH

مثال؟

A

enoxaparine

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10
Q

LMWH

وزن مولکولی میانگین؟

A

2000 - 6000

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11
Q

LMWH
تقاوت‌ها با هپارین؟
3 مورد

A

1) bioavailability بیشتر
2) مدت بیشتر عملکرد
3) پس تعداد تجویز کمتری میخواد

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12
Q

LMWH

چند بار در روز؟

A

1 or 2

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13
Q

LMWH

نحوه تجویز؟

A

subQ

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14
Q

فونداپارینوکس

چیه؟

A

small synthetic drug that contains the biologically active penta-saccharide present in unfractionated and LMW heparins

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15
Q

فونداپارینوکس

نجوه تجویز؟

A

SubQ

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16
Q

فونداپارینوکس

چند بار در روز؟

A

once

Pharmacology - Katzung (41 decks)

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