34: GERD & peptic ulcer disease Flashcards Preview

Woo And Robinson 2020 Advanced Pharmacotherapeutic for NP all chapters > 34: GERD & peptic ulcer disease > Flashcards

Flashcards in 34: GERD & peptic ulcer disease Deck (14)
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1
Q
  1. Gastroesophageal reflux disease may be aggravated by the following medication that affects lower esophageal sphincter (LES) tone:
  2. Calcium carbonate
  3. Estrogen
  4. Furosemide
  5. Metoclopramide
A
  1. Estrogen
2
Q
  1. Lifestyle changes are the first step in treatment of gastroesophageal reflux disease (GERD). Food or drink that may aggravate GERD include:
  2. Eggs
  3. Caffeine
  4. Chocolate
  5. Soda pop
A
  1. Caffeine
3
Q
  1. Metoclopramide improves gastroesophageal reflux disease symptoms by:
  2. Reducing acid secretion
  3. Increasing gastric pH
  4. Increasing lower esophageal tone
  5. Decreasing lower esophageal tone
A
  1. Increasing lower esophageal tone
4
Q
  1. Antacids treat gastroesophageal reflux disease by:
  2. Increasing lower esophageal tone
  3. Increasing gastric pH
  4. Inhibiting gastric acid secretion
  5. Increasing serum calcium level
A
  1. Increasing gastric pH
5
Q
  1. When treating patients using the “Step-Down” approach the patient with gastroesophageal reflux disease is started on _______ first.
  2. Antacids
  3. Histamine2 receptor antagonists
  4. Prokinetics
  5. Proton pump inhibitors
A
  1. Proton pump inhibitors
6
Q
  1. If a patient with symptoms of gastroesophageal reflux disease states that he has been self-treating at home with OTC ranitidine daily, the appropriate treatment would be:
  2. Prokinetic (metoclopramide) for 4 to 8 weeks
  3. Proton pump inhibitor (omeprazole) for 12 weeks
  4. Histamine2 receptor antagonist (ranitidine) for 4 to 8 weeks
  5. Cytoprotective drug (misoprostol) for 2 weeks
A
  1. Proton pump inhibitor (omeprazole) for 12 weeks
7
Q
  1. If a patient with gastroesophageal reflux disease who is taking a proton pump inhibitor daily is not improving, the plan of care would be:
  2. Prokinetic (metoclopramide) for 8 to 12 weeks
  3. Proton pump inhibitor (omeprazole) twice a day for 4 to 8 weeks
  4. Histamine2 receptor antagonist (ranitidine) for 4 to 8 weeks
  5. Cytoprotective drug (misoprostol) for 4 to 8 weeks
A
  1. Proton pump inhibitor (omeprazole) twice a day for 4 to 8 weeks
8
Q
  1. The next step in treatment when a patient has been on proton pump inhibitors twice daily for 12 weeks and not improving is:
  2. Add a prokinetic (metoclopramide)
  3. Referral for endoscopy
  4. Switch to another proton pump inhibitor
  5. Add a cytoprotective drug
A
  1. Referral for endoscopy
9
Q
  1. Infants with reflux are initially treated with:
  2. Histamine2 receptor antagonist (ranitidine)
  3. Proton pump inhibitor (omeprazole)
  4. Anti-reflux maneuvers (elevate head of bed)
  5. Prokinetic (metoclopramide)
A
  1. Anti-reflux maneuvers (elevate head of bed)
10
Q
  1. Long-term use of proton pump inhibitors may lead to:
  2. Hip fractures in at-risk persons
  3. Vitamin B6 deficiency
  4. Liver cancer
  5. All of the above
A
  1. Hip fractures in at-risk persons
11
Q
  1. An acceptable first-line treatment for peptic ulcer disease with positive H. pylori test is:
  2. Histamine2 receptor antagonists for 4 to 8 weeks
  3. Proton pump inhibitor bid for 12 weeks until healing is complete
  4. Proton pump inhibitor bid plus clarithromycin plus amoxicillin for 14 days
  5. Proton pump inhibitor bid and levofloxacin for 14 days
A
  1. Proton pump inhibitor bid plus clarithromycin plus amoxicillin for 14 days
12
Q
  1. Treatment failure in patients with peptic ulcer disease associated with H. pylori may be because of:
  2. Antimicrobial resistance
  3. An ineffective antacid
  4. Overuse of proton pump inhibitors
  5. All of the above
A
  1. Antimicrobial resistance
13
Q
  1. If a patient with H. pylori-positive peptic ulcer disease fails first-line therapy, the second-line treatment is:
  2. Proton pump inhibitor bid plus metronidazole plus tetracycline plus bismuth subsalicylate for 14 days
  3. Test H. pylori for resistance to common treatment regimens
  4. Proton pump inhibitor plus clarithromycin plus amoxicillin for 14 days
  5. Proton pump inhibitor and levofloxacin for 14 days
A
  1. Proton pump inhibitor bid plus metronidazole plus tetracycline plus bismuth subsalicylate for 14 days
14
Q
  1. After H. pylori treatment is completed, the next step in peptic ulcer disease therapy is:
  2. Testing for H. pylori eradication with a serum ELISA test
  3. Endoscopy by a specialist
  4. A proton pump inhibitor for 8 to 12 weeks until healing is complete
  5. All of the above
A
  1. A proton pump inhibitor for 8 to 12 weeks until healing is complete

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