Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology test 2 > ANS review > Flashcards

ANS review Flashcards

1
Q

Sympathetic

A

pregang in T1-L2-3, Intermediolateral horn of grey matter
postgang in ganglia
-paravertebral chain-either side of SC
-prevertebral ganglia-celiac, superior etc
*SHORT PRE long post

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Parasympathetic

A

pergang cranial CN3, 7, 9, 10 Sacral S2-4
postgang target organs
*long pre SHORT POST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

only innervated by SNS

A

sweat glands

blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

only innervated by PSNS

A

ciliary muscles of eye

bronchial smooth muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

both SNS and PSNS have baseline tone ex:

A

Vagal PSNS predominance–HR

SNS tone–blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SNS normal receptors

A

pre on Nicotinic with Ach
post on ADRENERGIC with NE
*SAN
adrenergic receptors alpha and beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PSNS normal receptors

A

pre on Nicotinic with Ach
post on Cholinergic-Muscarinic with Ach
*PCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cholinergic receptors

A

Nicotinic Ach: Nm-muscle Nn-Brain

Muscarinic Ach: M1-5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Adrenergic receptors

A

alpha 1,2

Beta 1,2,3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

SNS involuntary control of

A

EYE: myosis
BLOOD VESSELS: shunt blood to heart, skeletal muscles. shunt blood AWAY from skin, kidneys, GI
SALIVARY GLAND: off-dry mouth
HEART: strong contractility, fast HR-AV node
LUNGS: dilate
ADRENAL M: secrete Epi
LIVER: release energy breakdown glucose
GI: calm
BLADDER: relaxed
GENITALIA: relaxed
SWEAT GLANDS: increase sweat from increase heat skeletal muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

PSNS involuntary control of

A 
EYE: miosis
LACRIMAL GLAND: active, tears
SALIVARY GLAND: active, secreting
HEART: "relaxed" slow HR
LUNG: mild constriction
UPPER GI: active, pancreas, secreting 
LOWER GI: parastalsis
BLADDER: contracted 
GENITALIA: can no reproduce
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

SNS abnormal

A
  • Sweat glands: pre Nicotinic post Muscarinic all Ach (should be post adrenergic, and NE)
  • Adrenal Medulla: pre only Nicotinic Ach then releases Hormones: 20%NE 80%Epi
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Alpha 1’s Gprotein

A

GalphaQ-Excitatory, blood vessels

  1. PLC activated
  2. IP3 and DGA
  3. PKC and increased free Ca
    * stronger contraction, smooth muscle vasoconstriction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

alpha2’s Gprotein

A

Galpha i- inhibitory blood vessels, pre/postsynaptic

  1. inhibit adenylate cyclase
  2. decrease cAMP
  3. increase K conduction-hyperpolarize
    * smooth muscle contraction, hyperpolarize
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Beta 1,2,3’s Gprotein

A

GproteinS-Excitatory,

  1. activates adenylate cyclase
  2. Increase cAMP
    * relaxes smooth muscle, broncodilates, stimulates heart contractility and increased rate
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

cAMP does what

A

cause smooth muscle to relax,

17
Q

Alpha 1 locations

A 
most vascular smooth muscle: blood vessels, sphincter, bronchi--CONTRACT
Iris-radial muscle---MYDRASIS
Pilomoter smooth muscle--ERECT HAIR
Uterus--CONTRACT
Heart--CONTRACT
18
Q

Alpha 2 locations

A

Platelets–AGGREGATION
Adrenergic and cholinergic nerve terminals
PRE: neg feed back: INHIBIT NEUROTRANSMITTERS (DESREASE BP, HR)
GI—RELAXATION
CNS—DECREASE SNS OUTFLOW, SEDATION

19
Q

Beta 1 locations

A

Heart–INCREASE FORCE AND RATE OF CONTRACTILITY (SA, AV NODE)
Kidneys–STIMULATE RENIN RELEASE

20
Q

Beta 2 locations

A

Resp, Uterine, Vascular, GI, GU, Visceral sm–RELAXATION
Mast cells—DECREASE HISTAMINE RELEASE
skeletal muscle—K UPTAKE, DILATION, INCREASED SPEED OF CONTRACTION
Liver–GLYCOGENOLYSIS, GLYCONEOGENSIS
Pancreas—INCREASE INSULIN SECRETION
Adrenergic nerve terminals–INCREASE RELEASE OF NE

21
Q

Beta 3

A

Fat cells—ACTIVATES LIPOLYSIS, BREAK DOWN FAT.

22
Q

Dopamine 1

A

Smooth muscle post–DILATES, RENAL MESENTERIC, CORONARY, CEREBRAL BLOOD VESSELS

23
Q

Dopamine 2

A

Nerve endings pre—MODULATES TRANSMITTER RELEASE N/V INCREASED, PROMOTE N/V

24
Q

endogenous catecholamines

A

Epi, NE, Dopa

25
Q

Synthetic catecholamines

A

Isoproterenol, Dobutamine

26
Q

Synthetic Non-catecholamines 2 types

A

Indirect: Ephedrine, mephentermine, amphetamies
Direct: phenylephine, methoxamine

27
Q

Direct agonist

A

varied affinities for alpha 1,2 Beta 1,2,3

28
Q

Indirect agonist

A

increase release of Neurotransmitters

Pharmacology test 2 (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions