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Neurology - step > Brain Tumours > Flashcards

Brain Tumours Flashcards

1
Q

most common tumor in adults

A

glioblastoma multiforme

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2
Q

most common benign tumor in adults

A

menigioma

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3
Q

brain tumor associated with NF-2

A

meningioma and schwanomma

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4
Q

brain tumor associated with von hippel lindau

A

hemagioblastoma

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5
Q

malignant adult brain tumour

A

glioblastoma multiforme/ grade IV astrocytoma

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6
Q

adult brain tumors found in frontal lobes

A

glioblastoma multiforme (cerebral hemispheres) and oligodendrocytomas

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7
Q

brain tumor that can cross the corpus callosum

A

glioblastoma multiform/grade IV astrocytoma

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8
Q

GFAP positive brain tumor in adults

A

glioblastoma multiforme

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9
Q

S100+ brain tumor in adults

A

schwannoma

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10
Q

tumor found in convexities of hemispheres and parasagittal regions outside of the brain parenchyma

A

meningioma

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11
Q

cell of origin for meningiomas

A

archanoid cells

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12
Q

new onest of focal seizures

A

meningiomas

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13
Q

dural tail

A

meningiomas

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14
Q

cerebellar tumor in adults

A

hemangioblastoma

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15
Q

cerebellar and retinal tumors in adults suscept

A

von hippel lindaue

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16
Q

can produce polycythemia

A

hemagioblastoma

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17
Q

typically at cerebellopontine angle

A

schwanomma

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18
Q

bilateral schwanommas suspect

A

NF-2

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19
Q

resectbale or treated with sterotatcti radiosurgery

A

schwanommas

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20
Q

positive staingin in schwanomma

A

S100

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21
Q

relatively rare and slow growing adult brain tumor

A

oligodendroglioma

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22
Q

frontal lobe tumor

A

oligodendroglioma

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23
Q

chicken wire capillary patern

A

oligodendroglioma

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24
Q

adult brain tumor that calcifies

A

oligodendroglioma

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25
Q

bitemporal hemianopia

A

pituitary adenoma

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26
Q

sequelae of hyper or hypopituitarism

A

pituitary adenoma

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27
Q

name the tumor: fried egg celsl with round nuclie and clear cytoplasm, calcification and chichen wire capillary pattern

A

oligodendroglioma

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28
Q

name the tumor: along any peripheral nerve

A

schwanomma

29
Q

name the tumor: closely arranged, thin walled capillaries with minimal intervening parenchyma

A

hemangioblastoma

30
Q

name the tumor: spindle cells concentrically arranged in a whorled pattern with psammoma bodes/laminated calcifications and firm on gross

A

menigioma

31
Q

name the tumor: pseudopalisading pleomorphic tumor cells that border central areas of necrosis and hemorrhage

A

glioblastoma multiforme

32
Q

name the tumor: butterfly

A

glioblastoma multiforme

33
Q

name the most common brain tumor in children

A

pilocytic low grade astrocytoma

34
Q

name the most common malignant tumor in childre

A

medulloblastoma

35
Q

GFAP positive tumor in children

A

pilocytic low grade astrocytoma

36
Q

where are piloctyic low grade astrocytomas ususally found

A

in posterior fossa ie cerebellum

37
Q

pilocytic low grade astrocytoma is bening or maligi

A

bening

38
Q

describe appearance of low grade astrocytoma

A

well circumsribced with ROESTHAL FIBERS

cystic and solid

39
Q

what is a Rosenthal fibre

A

eosinophilic corkscrew fibres seen in pilocytic low grade astrocytomas usually in cerbelleum beign in children GFAP positive

40
Q

medulloblastoma benign or maligi

A

high maligi

41
Q

where is medulloblastoma located

A

cerebellum

42
Q

histo of medulloblastoma

A

primitive neuroectoderm tumor ventral in the cerebellum; HOMER WRITGHT ROSETTES
small cell
sold

43
Q

pathogen of medulloblastoma

A

compresses 4th ventricle and can lead to noncommunicating hydrocephalus

44
Q

what tumors in children can cause non communicating hydrocephalus

A

medulloblastoma and ependymoma

45
Q

what tumor can cause drop mets to the spinal cord

A

medulloblastoma

46
Q

which tumor in hcildre is hemorrhagic

A

medulloblastoma

47
Q

I say homer wright you think

A

medulloblastoma

48
Q

I say solid tumor you think

A

medulloblastoma

49
Q

location fo ependymoma

A

most commonly in the 4th ventrcile

50
Q

prognosis of ependymoma

A

poor

51
Q

describe histopathos of ependymoma

A

perivascular roesstes with rod shaped blepharoplasts/basal siliary bodies found near nucleus

52
Q

what is a bracniopahryngioma

A

bening childhood tumor derives from remants of trahtke pouch

53
Q

what is the most common childhood upratentorial tumor

A

craniopharygioma

54
Q

what two tumors present similarly with unquie visual changes

A

bitemporal hemanopia in craniopharygioma and pituitary ademona

55
Q

what three tumors calcify

A

meningioma
oligodendroglioma
craniopharyngioma

56
Q

histopathos of craniopahrymgioma pelase

A

tooth enale like calcifications

57
Q

what causes herniations

A

increase ICP and portion of brain can become displaced

58
Q

what herniation can compress the ACA

A

subfalcine hernation: cingulate gyrous moves under the falx cerberi

59
Q 
presentation:
left EOM problems
left dilation of pupil
left motor weakness
left occipital lobe infarct at pca
A

uncal herniation

60
Q

what happens in an uncal hernation

A

medial temporal lobe moves down into the tetorium cerebelli

61
Q

why do motor signs show up on same side as occipital symptoms in an uncal hernation

A

compresses contralateral crus – KERNOHAN NOTCH cuses a fals localization sign

62
Q

what dose compression of the PCA cause

A

ipsilateral PCA causes contralateral homonymous hemianopia - same side of brain affected

63
Q

what is kernohans notch

A

contralateral crus cecrebri - causes motor weakness on ipsilateral side

64
Q

what is consequents of downward transtenroial/central hreniation

A

caudal displacement of brain stem cau;ses DURET HEMORRHAGES - paramedian branches of the basilar artery - usually fatal

65
Q

duret hemorrhages associated with?

A

downward transtentorial/cenral herniation

66
Q

which two types of herniations are fatal

A

downward transtentoria;/central hernation (rips paramedian branches of basilar artery )
cerebellar tonsillar hernation into foramen mangeum - cardiorespiratory arrest

67
Q

what hernation causes cerebellar coning

A

cereberlal tonsillar herniation

68
Q

what hernation compresse the brain stem resulting in coma and death

A

cerebellar tonsil herniation into the foremane magnum.

69
Q

what passes through the foreamne magnum

A

spina roots of CN XI
brain stem
vertebral arteries

Neurology - step (10 decks)

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