Pharmacology Flashcards

1
Q

drugs ending in -zole ware what class

A

PPI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Misoprostol mechanism

A

PGE1 analog decreases acid production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Sulfasalazine toxicity

A

Reversible oligospermia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Metoclopramide mechanism

A

D2 blocker increases contractility and motility proximal to the colon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

bismuth, sucralfate clinical use

A

ulcer healing, traveler’s diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Misoprostol toxicity

A

diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Drugs ending in -dine are what class

A

H2 blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

MgOH toxicities

A
  1. Diarrhea
  2. decreased DTRs
  3. hypotension
  4. cardiac
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

CaCO3 toxicities

A
  1. hypercalcemia
  2. chelate and decrease efficacy of tetracyclines
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PPI toxicities

A
  1. increased C diff risk
  2. lowers Mg2+
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ondansetron toxicities

A
  1. prolonged QT
  2. HA
  3. constipation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ondansetron mechanism

A

5HT3 antagonist decerases vagal stimulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Bismuth, sucralfate mechanism

A

increases bicarb secretion at ulcer base

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Octreotide clinical use

A

variceal bleeds

acromegaly

VIPoma

carcinoid tumors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Misoprostol clinical use

A

prevent NSAID associated gastric ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Aluminum OH toxicities

A
  1. constipation
  2. hypophosphatemia
  3. proximal weakness
  4. osteodystrophy
  5. seizures
16
Q

Ranitidine toxicity

A
  1. Renal
17
Q

Orlistat clinical use

A

weight loss

18
Q

Sulfasalazine clinical use

A

IBD involving colon

19
Q

BMP abnormality 2/2 antacid use

A

hypokalemia

20
Q

Orlistat mechanism

A

inhibits lipase –> decreases fat absorption

21
Q

Cimetidine toxicities

A
  1. cytochrome P450 inhibitor
  2. antiandrogenic
  3. cross blood-brain barrier and placenta
  4. renal
22
Q

Metoclopromide toxicities

A
  1. Parkinsonism / tardive dyskinesia
  2. Interactions with digoxin and diabetic drugs