Dementia Flashcards

1
Q

Risk factors for vascular dementia

A

Smoking

HPT

Diabetes

Previous CVAs, MIs, TIAs IHD, PVD

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2
Q

Aphasia

A

Language and communication deficit

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2
Q

Difference between dementia and delirium

A

Dementia vs Delirium: Chronic vs acute

Insidious vs rapid

Progressive vs fluctuating

Long vs short duration

Level of consciousness - worse in delirium

Uncommon vs common hallucinations

Irreversible vs reversible

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2
Q

Pharmacological management of Alzheimer’s

A

HRT (in women)

Vitamin E

Cholinesterase inhibitors

Psychotropic agents for residual symptoms

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3
Q

Gross neuropathology in Alzheimer’s

A

Brian shrinkage

Enlarged ventricle

Deep sulci

Thinning of cortex

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4
Q

3 types of dementia

A

Cortical - intellectually based e.g. Alzheimer’s

Subcortical - movement based e.g. Parkinson’s

Fronto-temporal - behaviour based e.g. Pick’s

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4
Q

Neuronal changes in Alzheimer’s

A

Deposition of beta-Amyloid protein - extracellular plaques - neurofibrillary tangles

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5
Q

Risk factors for Alzheimer’s

A

Age

Family history

Head injury

Down’s syndrome

Epilepsy

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6
Q

Agnosia

A

Inability to recognise familiar objects/shapes

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8
Q

Apraxia

A

Inability to perform purposeful actions

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10
Q

Cognition

A

The process of obtaining, organising and using intellectual information

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11
Q

Which test do dementia patients score better on: MOCA or mini mental?

A

Mini mental

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12
Q

Under what DSM heading is dementia

A

Major Neurocognitive Disorder

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13
Q

3 characteristic criteria of cognitive deficits in dementia

A
  1. Interfere with independence in everyday activities
  2. Are not exclusively in the context of a delirium
  3. Not better explained by another mental disorder
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15
Q

Cognitive domains

A

CAL(L) ME PLS

Complex Attention

Learning and Memory

Executive function

Perceptual-motor

Language

Social cognition

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16
Q

Protective factors for Alzheimer’s

A

Oestrogen

Vitamin E

Low dose NSAIDs

Intellectual stimulation

17
Q

Difference in progression between Alzheimer’s and vascular dementia

A

Alzheimer’s - gradual continuous progression

Vascular dementia - stepwise progression

18
Q

Definition of dementia

A

Significant cognitive decline from a previous level of performance in one or more cognitive domains

19
Q

Ddx for acute loss of consciousness/delirium

A

AEIOU TIPS:

Alcohol

Epilepsy

Insulin

Overdose

Uraemia/Underdose

Trauma

Infections

Psychogenic

Stroke