Cytokines Flashcards
1
Q
IL-7
A
Differentiate cells of the lymphoid lineage: T cells, B cells, NK cells, NKT cells
2
Q
IL-3
A
Differentiate cells of the myeloid lineage (3M, GD):
Granulocytes: Neutrophils, Eosinophils, Basophils
Erythryocytes
Monocytes/Macrophages
Megakaryocytes
Dendritic Cells
3
Q
Macrophages produce
A
IL-1 and TNF-alpha
4
Q
Macrophage activator cytokine
A
IFN-gamma
5
Q
Released by neutrophils
A
IL-1: fever
IL-3: differentiates myeloid cells
TNF-alpha: acute inflammation
6
Q
Released by eosinophils
A
IL-3: differentiates myeloid cells
IL-5: causes further production of eosinophils
GM-CSF
7
Q
Released by basophils
A
IL-4: Causes IgM ab to switch to Ig EIL-13
8
Q
Released by mast cells
A
IL-3: Differentiates myeloid cells IL-4: Causes IgM ab to switch to Ig E IL-5: produces eosinophils IL-6: acute phase reactants IL-8: chemotactic cytokine IL-10: inflammatory cytokine
