Chapter 4.6-4.7

Question 0

List the classes of small-molecule neurotransmitters

Answer 0

Amino acids
Monoamines
Acetylcholine
Unconventional neurotransmitters

Question 1

What does the term “agonist” mean?

Answer 1

A drug that facilitates the effects of another drug

Question 2

List the two separate groups of Monoamines neurotransmitters

Answer 2

Catecholamines and indolamines

Question 3

Which monoanime neurotransmitters belong to each group?

Answer 3

Catecholamines- dopamine, epinephrine, and norepinephrine

Indolamines- serotonin

Question 4

What one class of neurotransmitters are considered large-molecule neurotransmitters?

Answer 4

Neuropeptides

Question 5

What is the most prevalent excitatory neurotransmitter in the mammalian CNS?

Answer 5

Glutamate

Question 6

What is the most prevalent inhibitory neurotransmitter?

Answer 6

GABA

Question 7

What are the seven general steps common to most neurotransmitters?

Answer 7

1) synthesis of the neurotransmitter
2) storage in vesicles
3) breakdown in the cytoplasm of any neurotransmitter that leaks from the vesicles
4) exocytosis
5) inhibitory feedback via autoreceptors
6) activation of postsynaptic receptors
7) deactivation

Question 8

Drugs preventing the reuptake of which monoanime neurotransmitter are used to treat depression?

Answer 8

Serotonin

Question 9

True or false. tolerance and withdrawal from a drug are different manifestations of the same underlying physiological change.

Answer 9

True

Question 10

List two families of endogenous opioids.

Answer 10

1) enkephalins

2) endorphins