Pathology of Rashes Flashcards

1
Q

What causes acne?

A
  1. Increased Androgens at puberty
  2. Increased Androgen sensitivity of sebaceous glands
  3. Keratin plugging of pilosebaceous units
  4. Infection with anaerobic bacterium corynebacterium acnes
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2
Q

What is Rosacea?

A
Commoner in females
Recurrent facial flushing
Visible blood vessels
Pustules
Thickening of skin - rhinophyma
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3
Q

What is the primary feature of IMMUNOBULLOUS DISEASES? Give 3 examples.

A

blisters
e.g. PEMHIGUS

BULLOUS PEMPHIGOID

DERMATITIS HERPETIFORMIS

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4
Q

What is the end result of Pemphigus vulgaris?

A

ACANTHOLYSIS

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5
Q

Is there acantholysis in Bullous pemphigoid

A

No

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6
Q

What has a Strong association with coeliac disease ?

A

dermatitis herpetiformis

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7
Q

Which is deeper, phemphigoid or phemphigus?

A

phemphigoiDDDDD (Deep)

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8
Q

Treatment of pemphigoid/pemphigus?

A

Systemic steroids
Other immunosuppressive agents: azathioprine, ciclosporin, mycophenolate
In pemphigoid: tetracycline antibiotics, nicotinamide
Topicals: emollients, topical steroids

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