[35] GI Polyps

Question 1

What are the types of GI polyps?

Answer 1

Inflammatory pseudopolyps
Hyperplastic polyps
Hamartomatous
Neoplastic

Question 2

What causes inflammatory pseudopolyps?

Answer 2

Regenerating islands of mucosa in UC

Question 3

What causes hyperplastic polyps?

Answer 3

Piling up of goblet cells and absorptive cells

Question 4

Describe the architecture of hyperplastic polyps

Answer 4

Serrated surface architecture

Question 5

Do hyperplastic polyps have any malignant potential?

Answer 5

No

Question 6

What are hamartomatous polyps?

Answer 6

Tumour-like growths composed of tissues present at site where they develop

Question 7

What causes hamartomatous polyps?

Answer 7

They may be sporadic, or part of familial syndromes

Question 8

What are neoplastic polyps?

Answer 8

Tubular or villous adenomas

Question 9

What symptoms might neoplastic polyps cause?

Answer 9

Are usually asymptomatic, but may cause blood/mucus on PR or tenesmus

Question 10

What is juvenile polyposis?

Answer 10

An autosomal dominant condition whereby patients have >10 hamartomatous polyps

Question 11

What is the importance of juveline polyposis?

Answer 11

There is an increased CRC risk, and so need surveillance and polypectomy

Question 12

What is Cowden syndrome?

Answer 12

An autosomal dominant syndrome with macrocephaly, skin stigmata, and intestinal hamartomas

Question 13

What does Cowden syndrome increase the risk of?

Answer 13

Extra-intestinal cancer