depression Flashcards
1
Q
another RF for bipolar
A
PMDD
lifetime SUD
2
Q
leading cause of mortality in depression by mortality atio observed over expected number of deaths
A
suicide!
don’t think this means that most die by suicide cuz its still only 10%
they have 5 yrs less life expectancy
3
Q
genes
A
serotonin transporter short allele redisposes to depression in respose to trauma, neurotocism, decreased SSRI response
BDNF Met (as apposed to Val) also predisposes to depression with lief events.
depression is 30% heritability (80% for BD)
4
Q
white matter lesions
A
related to late onset depression corerlates with mortality biggest RF is HTN vascular deprssion may need ECT less responsive to meds
5
Q
response rate after each try
A
25% L1
15% L2
5% L3
star D
6
Q
NNT for AA in depression
A
10
7
Q
Li and T3 best added to?
A
TCA
