IHC and associated tissue types Flashcards

1
Q

Keratin

A

Epithelium i.e. Carcinoma

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2
Q

Vimentin

A

Mesenchyme i.e. Sarcoma

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3
Q

Desmin

A

Muscle

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4
Q

GFAP

A

Neuroglia

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5
Q

Neurofilament

A

Neurons

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6
Q

PSA

A

Prostatic epithelium

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7
Q

ER

A

Breast epithelium

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8
Q

Thyroglobulin

A

Thyroid follicular cells

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9
Q

Chromogranin

A

Neuroendocrine cells

  1. Small cell CA of lung - worst
  2. Carcinoid tumors - best
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10
Q

S-100

A
  1. Melanoma
  2. Schwannoma
  3. Langerhans cell histiocytosis
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