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Pathology Pt. 4 > Buzzwords > Flashcards

Buzzwords Flashcards

1
Q

crew cut x-ray

A

thalassemia

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2
Q

hypersegmented neutrophils

A

any macrocytic-hyperchromic anemia but think folate or B12 deficiency

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3
Q

Fat in bone marrow

A

aplastic anemia

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4
Q

Macrocytic-hyperchromic anemia WITH neuro problems

A

B12 deficiency anemia

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5
Q

Macrocytic-hyperchromic anemia WITHOUT neuro problems

A

Folate deficiency anemia

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6
Q

too much EPO

A

secondary polycythemia

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7
Q

abnormal PML/RARA fusion protein

A

acute promyelocytic leukemia (a type of acute myelogenous leukemia)

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8
Q

no terminal differentiation of myeloid cells

A

acute myelogenous leukemia

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9
Q

proliferation of mature myeloid cells

A

chronic myelogenous leukemia

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10
Q

BCR-ABL fusion –> tyrosine kinase activation

A

chronic myelogenous leukemia

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11
Q

West Philadelphia born and raised chromosome

A

chronic myelogenous leukemia or B-acute lymphoblastic leukemia/lymphoma (children mostly)

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12
Q

MYC oncogene

A

Burkitt’s lymphoma

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13
Q

child with large tumor in jaw or face

A

Burkitt’s lymphoma

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14
Q

starry sky macrophages

A

Burkitt’s lymphoma

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15
Q

Reed Sternberg cells

A

Hodgkin lymphoma

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16
Q

punched-out skull lesions

A

multiple myeloma

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17
Q

viscous blood, red skin

A

polycythemia

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18
Q

trans-retinoic acid is used to treat….

A

acute promyelocytic leukemia

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19
Q

Bence Jones protein

A

multiple myeloma

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20
Q

prostate - peripheral zone

A

prostate cancer

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21
Q

prostate - transitional or central zone

A

BPH

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22
Q

no basal reserve cells

A

prostate cancer

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23
Q

Isolated humps between the glomerular BM and podocytes

A

Acute poststreptococcal glomerulonephritis

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24
Q

breaks in the BM, crescents formed by proliferated parietal cells

A

Crescentic glomerulonephritis

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25
Q

Anti Type IV collagen antibody

A

Goodpasture syndrome

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26
Q

leukocyte casts in urine

A

acute pyelonephritis

27
Q

proteinaceous casts in the distal convoluted tubules and collecting ducts

A

acute tubular necrosis

28
Q

Orphan Annie eye nuclei

A

Papillary thyroid carcinoma

29
Q

moon face

A

Cushing disease

30
Q

buffalo hump

A

Cushing disease

31
Q

striations on the skin of stomach

A

Cushing disease

32
Q

bite cells

A

G6PDH deficiency

33
Q

moth balls (napthalene)

A

G6PDH deficiency

34
Q

fava beans

A

G6PDH deficiency

35
Q

pencil/cigar-shaped cells

A

iron-deficiency anemia

36
Q

desmoplastic response

A

comedo DCIS (high grade) OR invasive ductal carcinoma

37
Q

CA-125

A

cystadenocarcinoma of the ovary

38
Q

signet ring cells

A

LCIS

39
Q

D cyclin dysregulation

A

multiple myeloma

40
Q

Erythoplasia of Queyrat

A

Bowen disease (carcinoma in situ of penis)

41
Q

prominent Leydig cells

A

cryptorchidism

42
Q

parchment/crinkled

A

lichen sclerosus of vulva

43
Q

chocolate cysts

A

endometriosis

44
Q

powder burns

A

endometriosis

45
Q

mutated mismatch repair and PTEN tumor suppressor gene

A

endometrioid carcinoma (type 1)

46
Q

whorls of smooth muscle cells

A

leiomyoma

47
Q

Ashkenazi Jewish women

A

BRCA2

48
Q

irregular kidney surface

A

autosomal dominant polycystic kidney disease

49
Q

smooth kidney surface

A

autosomal recessive polycystic kidney disease

50
Q

vanillylmandelic acid

A

phaeochromocytoma

51
Q

EBV in endemic cases

A

Burkitt lymphoma

52
Q

Keratin pearls

A

keratinizing squamous cell carcinoma of the vulva

53
Q

BCL6/BCL2 gene rearrangements

A

Diffuse large B cell lymphoma

54
Q

embryonal elements/mixed tumor in kidney

A

Wilms tumor

55
Q

cigarette smoking

A

urothelial carcinoma or Grave’s disease or acute promyelocytic leukemia

56
Q

coarse chromatin granules

A

cervical intraepithelial neoplasm (CIN) aka dysplasia

57
Q

nipple discharge

A

non-comedo DCIS or invasive ductal carcinoma

58
Q

perineural invasion

A

invasive ductal carcinoma

59
Q

desmoplastic response

A

invasive ductal carcinoma OR comedo DCIS

60
Q

dirty brown granular casts in urine

A

acute tubular necrosis

61
Q

schistosomiasis

A

urothelial carcinoma

62
Q

Gleevec

A

tx for CML (blocks tyr. kinase binding site)

63
Q

Disappearance of rete pegs

A

Lichen sclerosus of the vulva

Pathology Pt. 4 (10 decks)

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