Vitamins Flashcards
1
Q
Functions of Vitamin A
A
- Prosthetic group of visual pigments
- Nuclear modulator of gene expression
- differentiation of epithelial
2
Q
VItamin A deficiency
A
- night blindness
- dedifferentiation = poor appetite, poor growth,
- xerophthalmia
3
Q
Functions of Vitamin D
A
- maintain serum Ca & P concentrations
- increase intestinal absorption
- increase bone resorption
- increase renal reabsorption
4
Q
Vitamin D deficiency
A
- Rickets in children
- Osteomalacia
5
Q
Function of Vitamin E
A
- scavenger of free radicals and peroxyl radicals
- inhibition of platelet aggregation and increased vasodilation
6
Q
Function of Vitamin K
A
-regulation of blood clotting protein synthesis; 7 vitamin K-dependent proteins involved in coagulation
7
Q
Function of Thamin (B1)
A
- Coenzyme as TPP for aldehyde transfers
- Oxidative decarboxylation - pyruvate dehydrogenase
- Transketolase reactions in PPP
8
Q
Thiamin Deficiency
A
- Dry beriberi
- Wet beriberi
- Cerebral beriberi
9
Q
Dry beriberi
A
- peripheral neuropathy
- calf muscle tenderness
- bilateral wrist and ankle drop
- symmetric impairment of sensory, motor, and reflex functions
10
Q
Wet beriberi
A
- also called cardiac beriberi
- edema
- tachycardia
- cardiomegaly
- CHF
11
Q
Cerebral beriberi
A
- Wernicke’s enncephalopathy
- mental confusion
- 6th nerve paralysis & coma
12
Q
Riboflavin (B2)
A
-redox enzyme (FAD & FMN) in energy yielding reactions in CAC and b-oxidation (electron carriers for the enzymes)
13
Q
Riboflavin Deficiency
A
-sore throat, cheilosis, angular stomatitis, glossitis, seborrheic, dermatitis
14
Q
Niacin
A
-Coenzymes (NAD & NADP) in redox reactions, ATP synthesis, ADP ribose transfer reactions
15
Q
Niacin Deficiency
A
- Pellegra photosensitive dermatitis; symmetrical lesions on parts of body exposed to sun (except face)
- dermatitis, diarrhea, dementia, and death
