Skeletal Muscle Physiology Flashcards
What type of muscle is skeletal muscle?
Striated
Voluntary
What makes skeletal muscle striated?
Thick myocin filaments
Thin actin filaments
What makes skeletal muscle voluntary?
Innervated by somatic nervous system
What is the purpose of skeletal muscle?
posture movement respiratory movement heat production whole body metabolism
How are skeletal muscle fibres organised?
into motor units
What is a motor unit?
single alpha motor neuron
and all skeletal muscle fibres it innervates
Why do fibre numbers differ in motor units?
fewer units for fine movement
lots more unit for gross movement
What are the levels of organisation of skeletal muscle?
whole muscle
muscle fibre
myofibril
sarcomere
What is a myofibril?
Intracellular structure
contains actin and myosin
What is a sarcomere?
functional unit
contains actin and myosin
How is contraction initiated and propagated in a skeletal muscle?
Neurogenic initiation to contract motor units
Neuromuscular junctions propagate
NO GAP JUNCTIONS
What is a myofibril?
contractile intracellular structure
contains actin and myosin
What is a sarcomere?
functional unit
arrangement of actin and myosin
found between 2 Z lines (connecting thin filaments)
4 zones; A band, I band, H zone and M line
How does excitation contraction coupling work in skeletal muscle?
Ca2+ entirely
from sarcoplasmic reticulum
How does gradation of contraction occur in skeletal muscle?
by motor unit recruitment
summation of contractions