3.7.4. Introduction to the Kidney Flashcards Preview

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Flashcards in 3.7.4. Introduction to the Kidney Deck (4)
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1
Q

This condition is the number one cause of end stage renal disease

A

DM is #1 cause of end stage renal disease [ESRD] (on dialysis or transplant)

2
Q

Genetic marker related to ESRD (End stage renal disease)

A

Genetic marker: APOL1 gene polymorphism = 7-10X increased risk of ESRD

3
Q

Discuss the three types of renal injury

A

“Pre-renal”: lack of sufficient blood flow to the kidney

“Post renal”: mechanical obstruction of the ureters - usually anatomic

“Intra-renal” largest and most complex group, intrinsic diseases of the kidney. Seen with ischemia and toxins/drugs

4
Q

Kidneys are responsible for the conversion of 25-OH Vitamin D to ______.

A

Conversion of 25-OH Vitamin D to 1,25-OH Vitamin D