non-melanoma CA - SCC and variants

Question 1

who is affected by SCC

Answer 1

• white skin
• on sun exposed areas
• higher mortality than BCC

Question 2

what is SCC etiology

Answer 2

• kertinocyte
• UV exposure
• or arsenic
• immunocompromised

Question 3

clinical manifestations of SCC

Answer 3

morpho
- papule, plaque or nodule
- pink red or skin colored
- scale
- exophytic
- indurated
friable

Question 4

prog. of SCC

Answer 4

- mets rate is 5%
higher rates if
- large
- involves bone, muscle or nerve
- scalp, ears, nose, lip
- immunosuppressd
- caused by arsenic

Question 5

what is bowen’s disease

Answer 5

pre-malignant

• SCC in situ
• does NOT invade dermis

Question 6

what is actinic keratosis

Answer 6

• from kertinocyte

- pre-malignant - 1/1000 go to SCC

Question 7

etiolgy of AK

Answer 7

• cumulative sun exposure

- risk are: age, skin color, immunosupression, genes

Question 8

clinical manifestations of AK

Answer 8

• on sun exposed areas
• on backgroud of sun damages skin
• feels like sandpaper
• on lower lip is actinic cheilitis

Question 9

Tx of AK

Answer 9

local
- liquid nitro
- curettage
- shave
field
- 5-fu
- imiquimod

Question 10

what is keratocanthoma

Answer 10

• craterform, erythematous nodule with central core
• looks like volcano
• rapid growth, but oft spontaneously involutes