Affective Disorders

Question 1

The characteristics of mania are…

Answer 1

Euphoria 
Delusional 
Poor attention span 
Lack of sleep 
Self important

Question 2

Bipolar disorder is…

Answer 2

Alternating periods of mania and depression.
1% of the population is afflicted with this during their life
Equally frequent in men and women

Question 3

Unipolar disorder is…

Answer 3

Depression without mania
It is 2-3 times more likely in women then men
There are some rare cases of mania without depression

Question 4

Heritability

Rosenthal (1971)

Answer 4

10 times more likely to suffer an affective disorder if a close relative also does

Question 5

Heritability

Gershon (1976)

Answer 5

MZ concordance = 69%

DZ concordance = 13%

Question 6

Hertiability

Price (1968)

Answer 6

Concordance is the same whether twins are raised apart or together

Question 7

Pharmacology

MOA

Answer 7

Monoamine oxidase destroys monoamines in PoSN such as serotonin dopamine and noradrenaline

Question 8

Pharmacology

Iproniazid

Answer 8

Inhibits MOA so more neurotransmitters

Question 9

Treatment of depression

Answer 9

TB treatment used but nasty side effects
Replaced by tricyclic anti depressants which affect serotonin and noradrenaline
Now use SSRI and Prozac which affect serotonin

Question 10

Pharmacology

Lithium carbonate

Answer 10

Uses to treat mania as possibly stabilises serotonin release

Has side effects like hand tremors, weight gain and thirst

Question 11

Depression and sleep deprivation

Answer 11

Vogel (1990) preventing REM sleep acts as an anti depressant

Question 12

Depression and sleep deprivation

Answer 12

Sonerschlicht (1982) effects of 29 anti depressants. They all reduced REM sleep but increased SWS

Question 13

The characteristics of depression are…

Answer 13

Low energy levels 
Anhedonia (lack of normal enjoyment) 
Loss of appetite for food and sex 
Sleeping problems 
Constipation