Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology > Disease of Immunity > Flashcards

Disease of Immunity Flashcards

1
Q

Autoimmune Disease manifesting Ab’s against

M Protein cross react with cardiac tissues

A

Acute Rheumatic Fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Autoimmune Disease manifesting Ab’s against

Basement Membrane of Kidney and Lung

A

Good Pasture’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Autoimmune Disease manifesting Ab’s against

TSH Receptor

A

Grave’s Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Autoimmune Disease manifesting Ab’s against

Nicotinic Ach Receptor

A

Myasthenia Gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SLE AutoAb

A

ANA, Anti-dsDNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drug-induced Lupus AutoAb

A

Anti-Histone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Mixed Connective Tissue Disease AutoAb

A

Anti-RNP(ribonucleoprotein)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CREST Syndrome AutoAb

A

Anti-Centromere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

CREST Syndrome

A 
Calcinosis
Raynaud's Phen
Esophageal Dysmotility
Sclerodactyly
Telangiectasia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Diffuse Scleroderma AutoAb

A

Anti-Scl 70 (Anti topoisomerase)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Sjogren Sydrome AutoAb

A

Anti-SSA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Primary Biliary Cirrhosis AutoAb

A

Anti-mitochondrial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Autoimmune Hepatitis AutoAb

A

Anti-smooth muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Kawasaki Disease AutoAb

A

Anti-Endothelial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Wegener Granulomatosis AutoAb

A

Anti-Proteinase 3 (C-ANCA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Microscopic Polyangitis AutoAb

A

Anti-Myeloperoxidase (P-ANCA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Chrug Strauss AutoAb

A

Anti-Myeloperoxidase (P-ANCA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Hashimoto’s AutoAb

A

Anti-Thyroglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Microorganism implicated with GBS

A

Campylobacter Jejuni

20
Q

Demyelinating Neuropathy manifesting with

Ascending Neuromuscular Paralysis

A

GBS

21
Q

Management of Multiple Sclerosis

A

Anti-MBP Natalizumab

22
Q

Most Common cause of hypothyroidism in iodine sufficient areas

A

Hashimoto’s Thyroiditis

23
Q

___a Disease where it manifest when Gliandin stimulates cytotoxic attack on enterocyte causing ___

A

Celia Disease

Villous Atrophy

24
Q

SLE Criteria for diagnosis:

__ / 11

A

Serositis (Pericarditis, Pleuritis)
Oral ulcers
Arthiritis (Non erosive)
Photosensitivity

Blood dso (Hemolytic Anemia, Leukopenia, Lymphopenia, Thrombocytopenia)
Renal (GN Diffuse Proliferative)
ANA (+)
Immunologic (Anti dsDNA, Anti-Sm)
Neurologic (Sz, Psychosis)

Malar Rash
Discoid Rash

4/11

25
Q

Chronic disease characterized by Dry Eyes, Dry mouth, Arthritis

A

Sjogren Syndrome

26
Q

Triad of Sjogren Syndrome

A

Sicca
Keratoconjunctivitis
Xerostomia
Arthritis

27
Q

Immunologic Destruction of Lacrimal and Salivary Glands

A

Sjogren syndrome

28
Q

Drug used to treat Sjogren Syn

A

Corticosteroids
Artificial Tears
Pilocarpine

29
Q

Chronic Inflammation
Small Blood vessels
interstitial and perivascular fibrosis

A

Systemic Sclerosis

30
Q

4 types of Graft

A

Autograft - Self
Allograft - same Spp
Syngeneic Graft/Isograft - twin-twin
Xenograft - different species

31
Q

(3) Types of Rejection of Tissue Transplant

A 
Hyperacute Rejection
Acute Rejection
    AC
    AH
Chronic Rejection
32
Q

Most Common type of transplant Rejection

A

Acute Rejection

33
Q

Primary Bcell Immunodef

A

Bruton’s Agammaglobunemia
Selective IgA Def
Common Variable Immunodeficiency

34
Q

Primary T Cell immunodef

A

Di George Syndrome

Chronic Mucocutaneous Candidiasis

35
Q

Di George Syndrome (CATCH 22)

A 
Cardiac defect (TOF)
Abnormal facies
Thymic aplasia
Cleft palate
Hypocalcemia
22q11.2 chr. deletion
36
Q

Combined B - T cell Dso

A

SCID
Wiskott Aldrich Syndrome
Ataxia Telangiectasia

37
Q

Virtual Absence of Bcells due to Tyr Kinase Mutation

A

Bruton’s Agammagobinemia/ X-linked hypogammaglobinemia

38
Q

Failure of isotype switching

A

Selective IgA def

39
Q

Defect in Bcell maturation to plasma cell

A

Common variable immunodef

40
Q

profound deficit in t cells; failure of development of thymus and parathyroid glands

A

DiGeorge syn

41
Q

mutation in gene encoding for common gamma chain/IL 2 receptor gamma

A

SCID

42
Q

lack of NADPH oxidase failure of oxidative burst

A

CGD

43
Q

failure of phagolysosomal fusion faulty microtubules impair neutrophil chemotaxis

A

chediak higashi syndrome

44
Q

defective adhesion LFA1 on the surface of the phagocyte

A

Leukocyte adhesion defeciency

45
Q

deficiancy of c1 inhibitor leads to increase c3a, c5a

A

hereditary angioedema

46
Q

most common complement defect

A

C2 deficiency

Pathology (26 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions