Neuro J Bipolar Flashcards

1
Q

Bipolar 1

A

Mania plus depression

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2
Q

Bipolar 2

A

Hypomania plus Major depression

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3
Q

Cyclothymic disorder

A

Hypomania plus mild depression (dysthymia)

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4
Q

Bipoloar NOS

A

Antidepressent mania plus depression

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5
Q

Abnormal fight/flight

A

Amygdala

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6
Q

Impulsivity

A

Temporal love

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7
Q

Abnormal biologic rhythms

A

Hypothalamus

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8
Q

Abnormal mood states

A

Limbic system

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9
Q

Abnormal appetitive behavior

A

Hypothalamus

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10
Q

HPA axis

A

Hypothalamic Pituitary Adrenal axis

Increased activity associated with mania & depression

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11
Q

Secondary mania causes

A

Same as delirium (neuro diseases, infection, illness, drugs)

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12
Q

Secondary mania lesion (bipolar v unipolar)

A

subcortical v cortical

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13
Q

MRI neuropathology

A

Small PFC, amygdala, temporal lobe

Large ventricles

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14
Q

Hyperactive brain region

A

Cingulate gyrus

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15
Q

Catatonia Tx

A

Lorazepam, ECT

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16
Q

Bipolar Tx

1st line & 2nd line

A

Lithium

Valproic acid

17
Q

Atypical antipsychotic SE

A

Metabolic syndrome

18
Q

Typical antipsychotic SE

A

Extrapyramidal symptoms

19
Q

Treatment resistant Bipolar disorder

A

Not until ECT is completed