Proteins Flashcards

1
Q

CHON is called amphoteric because

A

Has positive and negative charges

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2
Q

CHON provide ______ of the total daily body energy requirement

A

12-20%

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3
Q

CHON are _______ of the cell’s dry weight

A

50-70%

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4
Q

Proteins come from greek word

A

“proteis”- first rank of importance

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5
Q

Actual 3-dimensional configuration of protein

A

Tertiary structure

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7
Q

Winding of the polypeptide chain: what structure?

A

Secondary structure

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8
Q

Glucogenic amino acids generate what precursors of glucose?

A

Pyruvate and citric avid cycle intermediates

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9
Q

Linear sequence of the amino acid

A

Primary structure

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10
Q

Balance between anabolism and catabolism

A

Nitrogen balance

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11
Q

Anabolism > catabolism

A

Positive Nitrogen Balance

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12
Q

Catabolism > anabolism

A

Negative Nitrogen Balance

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13
Q

Percent of nitrogen content in serum CHON

A

16%

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14
Q

CHON = _____ x N

A

6.25

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15
Q

Other name of prealbumin

A

Transthyretin

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16
Q

RV of prealbumin

A

18-45mg/dl

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17
Q

General transport CHON

A

Albumin

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18
Q

Folding pattern of protein

A

Tertiary structure

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19
Q

Serves a circulating reservoir of AA

A

Albumin

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20
Q

CHON that binds quinidine

A

a1- acid glycoprotein

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21
Q

Other name for alpha1- acid glycoprotein

A

Orosomucoid

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22
Q

Neutralizes neutrophil elastase that destroy lung alveoli

A

Alpha1-antitrypsin

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23
Q

Major inhibitor of protease activity

A

Alpha-1 antitrypsin

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24
Q

Transport T4T3 and retinol

A

Prealbumin

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25
Q

Maintains osmotic/oncotic pressure

A

Albumin

27
Q

CHON is synthesized in

A

Liver

28
Q

Lowest level of Albumin is seen in

A

Nephrotic syndrome

29
Q

Maternal serum AFP is done between

A

15 and 20 weeks of gestation

30
Q

As landmark to confirm that the specimen is CSF

A

Prealbumin

31
Q

Useful diagnostic tool in neonates with bacterial infections

A

Alpha-1 acid glycoprotein

32
Q

Half life of prealbumin

A

2 days

33
Q

Major form of PSA found in human sera

A

Alpha-1 antichymotrypsin

35
Q

CHON that is associated with Alzheimer’s disease

A

Alpha-1 antichymotrypsin

36
Q

Indicator of nutrition

A

Albumin

37
Q

Sensitive and highly prognostic marker of cystic fibrosis

A

Albumin

38
Q

Prealbumin is rich in

A

Tryptophan and 0.5% CHO

39
Q

Binds heme

A

Hemopexin

40
Q

Ceruloplasmin imparts what color in protein?

A

Blue

41
Q

Increase level of AFP is used to assess ______ of fetus

A

Neural tube effects

42
Q

For diagnosis of early hemolysis

A

Hemopexin

43
Q

Level of ceruloplasmin in Wilson’s diease

A

0.1 g/L

44
Q

Copper deposition in cornea of Wilson’s disease is what you called?

A

Kayser-Fleisher rings

45
Q

Reference value for Ceruloplasmin

A

18-45mg/dL

46
Q

B2- microglobulin is needed in production of what cells

A

CD8 cells

47
Q

CHON with affinity to vitamin D and actin

A

Group-specific component globulin

48
Q

Alpha-1 antichymotrypsin is a serine proteinase with

A

Cathepsin G

49
Q

Other name of transferrin

A

Siderophilin

50
Q

Light chain component of HLA

A

B2- microglobulin

51
Q

Alpha-2 macroglobulin inhibits

A

Trypsin, pepsin and plasmin

52
Q

Major component of B2- microglobulin

A

Transferrin

53
Q

Early warning test for person at risk of coronary artery disease

A

CRP

54
Q

Marker for long term prognosis of cardiovascular disease

A

Fibrinogen

55
Q

Most abundant complement in serum

A

C3

56
Q

CHON that is important in pathogenesis of age-related macular degeneration

A

C3

57
Q

Has greatest affinity to progesterone

A

Alpha-1 acid glycoprotein

58
Q

Gold standard in acute coronary syndrome

A

Troponin

59
Q

General scavenger molecule

A

CRP

61
Q

In extensive coagulation, fibrinogen is

A

Decrease

63
Q

CHON helps in evaluation of Intravascular hemolysis

A

Haptoglobin

66
Q

Ketogenic Amino acids are degraded to

A

Acetyl CoA