Renal Physiology Flashcards

1
Q

Most powerful trigger for ADH secretion

A

Increased plasma osmolarity

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2
Q

Effect of alcohol on ADH secretion

A

decrease ADH secretion, increase urine volume

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3
Q

Effect of ANP, BNP on urine secretion

A

Dec Na reabsorption

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4
Q

Effect of catecholamines on urine

A

Inc water reabsorption, inc Na reabsorption

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5
Q

Peritubular capillary hydrostatic pressure is decreased by

A

afferent and efferent arteriole vasocostriction

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6
Q

Peritubular capillary oncotic pressure is increased by

A

Plasma protein concentration and filtration fraction

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7
Q

Substance with the highest renal clearance

A

PAH > K > Creatinine > inulin > Urea > Na > Glucose, Amino acids

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8
Q

Rate at which substances are removed from blood in the kidneys

A

Renal clearance

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9
Q

Substance whose clearance is used to estimate GFR

A

inulin, BUN, Crea

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10
Q

Substance whose clearance is used to estimate renal blood flow and renal plasma flow

A

PAH

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11
Q

Substances filtered and partually reabsorbed have clearance __ than the GFR

A

less

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12
Q

Substances filtered and with net secretion have a clearance __ than the GFR

A

greater

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13
Q

Causes of High Anion Gap Metabolic Acidosis

A
Methanol
Uremia 
DKA
Paraldehyde, Propylene Glycol
Iron, Isoniazid, Idiopathic Acidosis
Lactic Acidosis
Ethylene Glycol, Ethanol
Salicylic Acid
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14
Q

Causes of Normal Anion Gap Metabolic Acidosis

A
Hyperalimentation
Acetazolamide
Renal Tubular Acidosis
Diarhea
Ureteroenteric Fistula
Pancreaticoduodenal Fistula
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15
Q

pH that is compatible with life

A

6.8-8.0

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16
Q

Normal pH of the Gastric Hcl

A

0.8(1-3 Guyton)

17
Q

H+ regulatory systems

A

body fluid buffer system(fastest)
respiratory center
kidneys

18
Q

Renal regulation of Acid-base balance(3)

A

secretion of excess H+
reabsorption of filtered HCO3
production of new HCO3 by using Ammonia and phosphate

19
Q

Vomiting will result in what acid-base abnormality

A

Metabolic Alkalosis(decreased ventilation)

20
Q

COPD will result in what acid-base abnormality

A

Respiratory Acidosis

21
Q

Pneumonia will result in what acid-base abnormality

A

Respiratory Alkalosis(increased ventilation)

22
Q

Vomiting will result in what acid-base abnormality

A

Metabolic Alkalosis(decreased ventilation)

23
Q

COPD will result in what acid-base abnormality

A

Respiratory Acidosis

24
Q

Pneumonia will result in what acid-base abnormality

A

Respiratory Alkalosis(increased ventilation)