Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Cancer Drugs > Flashcards

Cancer Drugs Flashcards

1
Q

Rescue for methotrexate

A

Leucovirin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Inhibits thymidilate synthase

A

5 FU

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

“Rescue” for 5 FU

A

Uridine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Causes panyctopenia and cerebellar dysfunction

A

Cytarabine

Arabynofuranosyl cytidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Decreases de novo purine synthesis

A

Azathioprine
6MP
6TG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drug for SLE

A

Azathioprine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Increased toxicity with allopurinol

A

Azathioprine

6MP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Uses for Dactinomycin

A

Wilma tumor
Ewing sarcoma
Rhabdomyosarcoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Causes cardio toxicity

A

Doxorubicin

Trastuzumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Causes pulmonary fibrosis

A

Bleomycin

Busulfan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Drugs for testicular CA

A

Bleomycin
Ego posive
Vinblastine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Causes hemorrhagic cystitis

A

Cyclophosphamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Antidote for cyclophosphamide

A

Mesna

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Crosses the BBB

A

Nitrosoureas-carmustine, lomustine, semustine, steptozocin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Acts on the M phase

A

Vinca alkaloids

Taxols

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Causes neurotoxicity

A

Vincristine

17
Q

Acts on the M phase and causes bone marrow suppression

A

Vinblastine

18
Q

For ovarian and breast CA

A

Paclitaxel and other taxols

19
Q

Hyperstabilize polymerized microtubule a in M phase

A

Paclitacel and another taxols

20
Q

Causes Nephrotoxicity and acoustic nerve damage

A

Cisplatin, carboplatin

21
Q

Prevent Nephrotoxicity through scavenging free radicals

A

Amifostine

22
Q

Inhibits topoisomerase II - DNA degradation

A

Etoposide, teniposide

23
Q

Inhibits topoisomerase I - prevent DNA unwinding and replication

A

Irinotecan, topotecan

24
Q

For colon CA

A

Irinotecan

25
Q

For small cell lung CA

A

Topotecan

26
Q

Inhibits ribonucleotide reductase - decreases DNA synthesis

A

Hydroxyurea

27
Q

Selective estrogen receptor modulator

A

Tamoxifen, raloxifen

28
Q

For breast CA, causes endometrial CA

A

Tamoxifen

29
Q

Prevents osteoporosis

Endometrial antagonist

A

Raloxifen

30
Q

Monoclonal antibody against HER 2

A

Trastuzumab (Herceptin)

31
Q

Tyrosine kinase inhibitor of bcr-abl and c-kit

A

Imatinib (Gleevec)

32
Q

Treatment for CML and GIST

A

Imatinib

33
Q

Monoclonal antibody against CD 20

A

Rituximab

34
Q

Treatment for NHL, RA, ITP

A

Rituximab

35
Q

Causes progressive multifocal leukoencephalopathy

A

Rituximab

36
Q

Treatment for metastatic melanoma

A

Vemurafenib

37
Q

Monoclonal antibody against VEGF

A

Bevacizumab

38
Q

Inhibits dihydrofolate reductase

A

Methotrexate

Pharmacology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions