3rd Year Drugs Flashcards

1
Q

Cilazapril

A
Inhibace
Angiotensin Converting Enzyme Inhibitor
1
Tabs: 1, 2.5, 5 mg
Hypertension, congestive Heart Failure
Contra: angioedema 
Brand: P generic: F; yes REF also captopril, quinapril, and ramipril
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2
Q

Enalapril

A
Vasotec
ACEI
1
Tabs: 2.5,5,10,20 mg.   IV: 1.25mg/ml
Hypertension, congestive heart failure
Contra: Angioedema
Brand: p; generic: p* RDP (ref drugs: cilazapril, captopril, quinapril, ramipril)
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3
Q

Fosinopril

A
Monopril
ACEI
1
Tabs: 10,20 mg
Hypertension, congestive heart failure
Contra: angioedema
Brand:p  generic:p* RDP (ref: cilazapril, quinapril, captopril, ramipril)
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4
Q

Lisinopril

A

Prinivil, Zestril
ACEI
1
Tabs: 5,10,20mg
Hypertension, congestive heart failure, post acute myocardial infarction
Contra: angioedema
Brand: p generic: p* RDP (ref: cilazapril, captopril, quinapril, ramipril)

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5
Q

Perindopril

A
Coversyl
(ACEI)
1
Tabs: 2,4,8mg
Hypertension, congestive heart failure
Contra: angioedema
P* RDP (ref: cilazapril,captopril,quinapril, ramipril)
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6
Q

Perindopril/Indapamide

A

Coversyl Plus, Coversyl Plus HD, Coversyl Plus LD
ACEI+Diuretic
1
Tabs: 4mg/1.25mg(plus); 8mg/2.5mg(plus HD); 2mg/0.625mg(plus LD)
Hypertension
Contra: Angioedema+See Indapamide
N/a

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7
Q

Quinapril

A
Accupril
ACEI
1
Tabs: 5,10,20,40mg
Hypertension, congestive heart failure
Contra: angioedema
REF: F(including brand)
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8
Q

Ramipril

A
Altace
ACEI
1
Caps: 1.25,2.5,5,10,15mg
Hypertension, congestive heart failure
Contra: angioedema
REF: brand: p; generic: f
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9
Q

Candesartan

A
Atacand
Angiotensin2 AT1receptor blocker
1
Tabs: 4,8,16,32mg
Hypertension
Contra: n/a
Brand:p; generic: f
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10
Q

Candesartan+hydrochlorothiazide

A

Atacand plus
Angiotensin2 AT1 receptor blocker+Diuretic
1
Tabs: 16/12.5mg; 32/12.5mg; 32/25mg
Hypertension
Contra: complete renal shutdown, severe hyponatremia, hypokalemia, hypovolemia, hypotension, hypersensitivity to sulphonamides.
Brand: p generic: f

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11
Q

Irbesartan

A
Avapro
Angiotensin2 AT1Receptor Blocker
1
Tabs: 75,150,300mg
Hypertension
Contra: n/a
Brand: p generic: f
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12
Q

Irbesartan+Hydrochlorothiazide

A

Avalide
Angiotensin2 AT1 receptor blocker+Diuretic
1
Tabs: 150/12.5mg, 300/12.5mg, 200/25mg
Hypertension
Contra: complete renal shutdown,severe hyponatremia, hypokalemia, hypovolemia, hypotension, hypersensitivity to sulphonamides.
Brand: p generic: f

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13
Q

Losartan

A
Cozaar
Angiotensin2 AT1 receptor antagonist
1
Tabs: 25,50,100mg
Hypertension
N/a
Brand: p generic: f
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14
Q

Losartan+hydrochlorothiazide

A
Hyzaar, Hyzaar DS
Angiotensin2 AT1receptor blocker+Diuretic
1
Hyzaar tabs: 50/12.5mg, 100/12.5mg
Hyzaar DS: 100/25mg
Hypertension
Contra: complete renal shutdown, severe hyponatremia, hypokalemia, hypovolemia, hypotension, hypersensitivity to sulphonamides.
Brand: p generic: f
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15
Q

Telmisartan

A
Micardis
Angiotensin2 AT1Receptor Blocker
Tabs: 40,80mg
Hypertension
Contra: n/a
Brand: p generic: f
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16
Q

Telmisartan+hydrochlorothiazide

A

Micardis Plus
Angiotensin2 AT1receptor blocker+Diuretic
1
Tabs: 80/12.5mg,80/25mg
Hypertension
Cotra: complete renal shutdown, severe hyponatremia, hypokalemia, hypovolemia, hypotension, hypersensitivity to sulphonamides.
Brand:p generic:full

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17
Q

Valsartan

A
Diovan
Angiotensin2 AT1receptor blocker
1
Tabs: 40,80,160,320mg
Hypertension
Contra:n/a
Brand:p generic: f
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18
Q

Valsartan+hydrochlorothiazide

A

Diovan-HCT
Angiotensin2 AT1receptor blocker+Diuretic
1
Tabs:80/12.5mg, 160/12.5mg, 160/25mg, 320/12.5mg,320/25mg
Hypertension
Contra: complete renal shutdown, severe hyponatremia, hypokalemia, hypovolemia, hypotension, hypersensitivity to sulphonamides.
Brand: p generic:f

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19
Q

Atenolol

A
Tenormin
B blocker
1
Tabs: 25,50,100mg
Hypertension, angina pectoris
Contra: sinus bradycardia, 2nd &3rd degree AV block, sick sinus syndrome, right ventricular or uncontrolled heart failure, cardio genic shock,hypotension, severe peripheral arterial disorders.
P
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20
Q

Bisoprolol

A
Monocor(brand dc), Sandoz-Bisoprolol
B blocker
1
Tabs: 5,10 mg
Hypertension
Cona: Sinus bradycardia, 2nd Nd 3rd degree AV block, cardiogenic shock, overt heart failure, right ventricular failure, 2dary pulmonary hypertension
F
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21
Q

Metoprolol

A

Betaloc, Lopresor, apo-metoprolol,apo-metoprolol (type L), Sandoz Metoprolol Injection
B blocker
1
Tabs:25,50,100mg Lopresor SR tabs:100,200mg IV: 1mg/ml
Hypertension, angina pectoris, MI
Contra: Sinus bradycardia, 2nd and 3rd degree AV block, sick sinus syndrome, right ventricular or uncontrolled heart failure, cardiogenic shock, hypotension, severe peripheral arterial disorder.
P

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22
Q

Propranolol

A

Apo-propranolol,Inderal-LA,Sandoz-Propranolol injection
B blocker
1
Tabs: 10,20,40,80,120mg; LA Capsules: 60,80,120,160mg; IV:1mg/ml
Hypertension, angina pectoris
Contra: bronchospasm. Bronchial asthma, allergic rhinitis during pollen season, sinus bradycardia, >1 AV block, cardiogenic shock, CHF, right ventricular failure secondary to pulmonary hypertension.
F

23
Q

Amlodipine

A
Norvasc
Calcium antagonist(dihydropyridine class) 
1
Tabs: 2.5,5,10mg
Hypertension, chronic stable angina, 
Contra: severe hypotension(SBP<90mmHg) 
RDP, REF: felodipine (p*)
24
Q

Diltiazem

A

Cardizem(brand dc), Cardizem CD, Tiazac, Tiazac XC, Sandoz-diltiazem injection
Calcium antagonist
1
Tabs:30,60; CD caps:120,180,240,300mg; Tiazac caps/Tiazac XC tabs: 120,180,240,300,360mg; IV: 5mg/ml
Angina, hypertension
Contra: sick sinus syndrome, 2nd or 3rd degree AV block, hypotension (SBP<90mmHg), MI patients with left ventricular failure
P(brand CD or ER Tab) F (all generic brands/tabs)

25
Q

Nifedipine

A

Adalat(brand dc),Apo-Nifed, Adalat PA(brand dc), Apo-Nifed PA, Adalat XL
Calcium Antagonist(dihydropyridine class)
1
Caps: 5,10mg, SR tabs:10,20mg, XLtabs: 20,30,60mg
Hypertension,Chronic stable angina
Contra: severe hypotension, pregnancy, lactation
RDP, REF: felodipine P*: for all except Adalat XR 60 mg(P)

26
Q

Verapamil

A

Isoptin-SR, Apo-Verap, Sandoz-Verapamil Injection
Calcium Antagonist
1
SR tabs:120,180,240mg, Apo-Verap:80,120mg IV:2.5mg/ml
Hypertension
Sick sinus syndrome, 2nd or 3rd degree AV block, hypotension(SBP<90mmHg), MI patients with left ventricular failure.
F ( all except Isoptin SR-P)

27
Q

Furosemide

A

Lasix, Lasix oral solution, Sandoz-furosemide injection
Loop diuretic
1
Tabs: 20,40,80; oral solution:10mg/ml, IV: 10mg/ml
Edema associated with CHF, cirrhosis of the live, and renal disease, hypertension
Contra: complete renal shutdown, severe hyponatremia, hypokalemia, hypovolemia, hypotension.
F (except Lasix P)

28
Q

Hydrochlorothiazide

A

HydroDiuril(brand dc) Apo-Hydro
Thiazides diuretic
1
Tabs:12.5,25,50,100mg
Edema associated with CHF, cirrhosis of the liver,and renal disease, hypertension
Contra: Complete renal shutdown, severe hyponatremia, hypokalemia, hypovolemia, hypotension, hypersensitivity to sulphonamides
F

29
Q

Hydrochlorothiazide+Triamterene

A

Dyazide(brand dc), Apo-Triazide
Thiazide+potassium sparing diuretic
1
Tabs: (Triamterene 50mg+HCTZ25mg)
Edema associated with CHF, cirrhosis of the liver, and renal disease, hypertension.
Contra: renal or hepatic dysfunction; combination therapy with other K+sparing agents; hypersensitivity to sulphonamides.
F

30
Q

Indapamide

A
Lozide
Diuretic( similar to thiazides) 
1
Tabs: 1.25,2.5mg
Hypertension 
Contra: Anuria: progressive and severe oliguria, hepatic coma, hypersensitivity to sulphonamides 
SA, F(except Lozide brand-P)
31
Q

Spironolactone

A

Aldactone
Aldosterone antagonist
1
Tabs: 25,100mg
Primary hyperaldosteronism,edema in CHF, Cirrhosis of the liver with edema and or ascites associated, nephrotic syndrome, hypertension, hypokalemia
Contra: Anuria, acute renal insufficiency, significant impairment of renal function, hyperkalemia, Addison’s disease.
F (brand is P)

32
Q

Atorvastatin

A
Lipitor
HMG-CoA Reductase Inhibitor
1
Tabs:10,20,40,80mg
Dyslipidemias
Contra: active liver disease, unexplained persistent serum transaminases elevations>3 times the upper limit of normal (ULN)
F (brand is P)
33
Q

Ezetimibe

A
Ezetrol
Cholesterol absorption inhibitor
1
Tab:10mg
Dyslipidemias
Contra:n/a
Not LCA
34
Q

Fenofibrate

A

Lipidil EZ, Lipidil Micro, Lipidil Supra, Apo-Fenofibrate
Fibrate
1
EZtab: 48,145mg; Apo-feno-micro: 67,200mg; Supra tab: 100,160mg; Apo-feno-super: 100,160mg, Apo-fenofibrate:100mg
Dyslipidemias
Contra: hepatic or severe renal dysfunction, pre-existing gallbladder disease, photoallegy or phototoxic reaction during tx with fibrates or to ketoprofen.
F(except Lipidil brand-P)

35
Q

Pravastatin

A
Pravachol
HMG-CoA Reductase Inhibitor
1
Tabs: 10,20,40mg
Dyslipidemias
Contra: Active liver disease, unexplained persistent serum transaminases elevations>3times ULN
F (brand P)
36
Q

Rosuvastatin

A
Crestor
HMG-CoA Reductase inhibitor
1
Tabs: 5,10,20,40mg
Dyslipidemias
Contra: active live disease, unexplained persistent serum transaminases elevations>3times ULN
F (brand P)
37
Q

Simvastatin

A
Zocor
HMG-CoA Reductase inhibitor
1
Tabs: 5,10,20,40,80mg
Dyslipidemias
Contra:active liver disease, unexplained persistent serum transaminases elevations >3times ULN.
F(except brand P)
38
Q

Clopidogrel

A

Plavix
Platelet aggregation inhibitor
1
Tabs: 75mg
Secondary prevention of MI, stroke, vascular death
Contra: active bleeding such as peptic ulcer and intracranial hemorrhage, significant liver impairment or cholestatic jaundice
In LCA

39
Q

Digoxin

A
Toloxin, Sandoz-Digoxin Injections
Cardiotonic glycoside
1
Tabs:0.0625,0.125, 0.25mg; oral solution:0.05mg/ml; IV (pediatric): 0.05mg/ml IV: 0.25mg/ml
Congestive heart failure, atrial fib
Contra: ventricular fibrillation
Not in LCA
40
Q

Isosorbide-5-mononitrate

A

Imdur
Nitrate (antianginal)
1
Extended-release tabs:60mg
Prevention of angina (not for acute attacks)
Contra: acute circulatory failure, postural hypotension, obstruction-related myocardial insufficiency, increased intracranial pressure, severe anemia, concomitant sildenafil
In LCA (RDP): REF isosorbide dinitrate tab

41
Q

Nitroglycerin (NTG)

A

Minitran, Nitro-Dur, Nitrolingual pumpspray, Nitrostat, Transderm Nitro
Nitrate vasodilator
1
Transdermal patches:0.2,0.4,0.6,0.8 mg/hr; SL tabs: 0.3,0.6mg; Pumpspray: 0.4mg/dose
Angina
Contra: severe anemia, increased intraocular pressure, increased intracranial pressure, hypotension, concomitant sildenafil.
Only spray in LCA

42
Q

Warfarin

A

Coumadin
Anticoagulant
1
Tabs:1,2,2.5,3,4,5,6,7.5,10mg
Prophylaxis and or tx of venous thromboembolism and pulmonary embolism
Contra: any condition where the hazard of hemorrhage is greater than the benefit of tx
In LCA

43
Q

Conjugated Estrogens

A

Premarin
Estrogenic hormones
1
Tabs: 0.3,0.625,1.25mg; vaginal cream: 0.625mg/g
Relief of menopausal and post menopausal sxs, atrophic vaginitis
Contra: estrogen-dependent cancers, undiagnosed abnormal vaginal bleeding, pregnancy, active hepatic dysfunction, thromboembolic disease, endometrial hyperplasia.
In LCA

44
Q

Estradiol-17 Beta

A
Estraderm, Estradot
Estrogenic hormone
1
Transdermal patches: 
Estradot: 25,37.5,50,75,100mcg/day
Estraderm: 25,100mcg/day
Relief of menopause and post menopausal sxs,prevention of osteoporosis
Contra: estrogen-dependent cancers, undiagnosed abnormal vaginal bleeding, pregnancy,active hepatic dysfunction, thromboembolic disease, endometrial hyperplasia
In LCA
45
Q

Estradiol-17 Beta (micronized)

A

Estrace
Estrogenic hormone
1
Tabs:0.5,1,2mg
Symptomatic relief of menopausal symptoms
Contra: estrogen-dependent cancers, undiagnosed abnormal vaginal bleeding, pregnancy, active hepatic dysfunction, thromboembolic disease, endometrial hyperplasia.
Not in LCA

46
Q

Estradiol-17Beta Hemihydrate

A

Estrogel
Estrogenic hormone
1
Each metered actuation delivers 1.25g of gel=0.75mg of estradiol-17beta
Relief of menopausal and postmenopausal sxs
Contra: estrogen-dependent cancers, undiagnosed abnormal vaginal bleeding, pregnancy, active hepatic dysfunction, thromboembolic disease, endometrial hyperplasia.
Not in LCA

47
Q

Ethinyl Estradiol/Cyproterone Acetate

A

Diane-35
Acne therapy (provides reliable contraception but should not be solely prescribed for this use). avoid concomitant use with other oral contraceptives
1
Tabs:no need to know strength
For tx of severe acne in women unresponsive to other txs.
Contra: history of actual thrombophlebitis, cerebrovascular disorders, MI,coronary arterial disease,liver tumors, estrogen-dependent cancers, severe diabetes with vascular changes.
Not LCA

48
Q

Ethinyl estradiol/ desogestrel

A
Marvelon, ortho-cept
Oral contraceptive
1
Tabs:na
Contraception control
Contra: history or actual thrombophlebitis,cerebrovascular disorders, MI, coronary, arterial disease, liver tumors, estrogen dependent cancers, severe HT, diabetes with vascular changes
In LCA
49
Q

Ethical estradiol/drospirenone

A
Yasmin
Oral contraceptive
1
Tabs
Conception control
Contra: history of actual thrombophlebitis,cebrovascular disorders,MI, coronary arterial disease, liver tumors, estrogen-dependent cancers, severe HT, diabetes with vascular changes
Not in LCA
50
Q

Ethinyl estradiol/levonorgestrel

A
Alesse, Min-Ovral, Triquilar
Oral contraceptive
1
Tabs
Conception control
Contra: history of actual thrombophlebitis, cerebrovascular disorders, MI, coronary atrial disease, liver tumors, estrogen dependent cancers, severe HT, diabetes with vascular changes
In LCA
51
Q

Ethinyl estradiol/norgestimate

A
Cyclen, Tri-Cyclen, Tri-Cyclen LO
Oral contraceptive
1
Tabs
Conception control
History of actual thrombophlebitis, cerebrovascular disorders, MI, coronary arterial disease, live tumors, estrogen dependent cancers, severe HT, diabetes, with vascular changes
Not in LCA
52
Q

Levothyroxine

A

Eltroxin, Synthroid
Thyroid hormone replacement
1
Tabs: Eltroxin: 50,100,150,200mcg; Synthroid: 25,50,75,88,100,112,125,137,150,175,200,300mcg
Hypothyroidism
Contra:untreated thyrotoxicosis; acute MI, uncorrected adrenal insufficiency
Not in LCA

53
Q

Medroxyprogesterone

A

Depo-Provera, Provera
Progestogen
1
Tabs: 2.5,5,10,100mg; IM injection: 50mg/ml,150mg/ml
Hormonal replacement therapy, adjunctive or palliative tx for endometrial breast cancer; Depo-Provera: conception control, tx of endometriosis
Contra: thrombophlebitis, thromboembolic disorders, undiagnosed vaginal/urinary tract bleeding; breast/endometrial cancer, hepatic dysfunction
In LCA

54
Q

Progesterone (Micronized)

A

Prometrium
Progestin
1
Caps:100mg
Adjunct to estrogen therapy in females with intact uterus
Contra: seve liver disease, unexplained abnormal vaginal bleeding, breast/endometrial malignancy, thrombophlebitis, peanut allergy
Not in LCA