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Antibiotics > Protein Synthesis Inhibitors > Flashcards

Protein Synthesis Inhibitors Flashcards

1
Q

What is the Method of Action for Tetracyclines?

A

Interferes with bacterial 30S ribosome protein production

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2
Q

What drugs are tetracyclines?

A

Doxycycline [Vibramycin] & Tetracycline

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3
Q

What is the MOA for macrolides?

A

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis

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4
Q

What drugs are macrolides?

A

Erythromycin [E.E.S.],
Clarithromycin [Biaxin],
Azithromycin [Zithromax]

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5
Q

What is the MOA for Ketolides?

A

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis

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6
Q

What drug is a Ketolide?

A

Telithromycin [Keteck]

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7
Q

What is the MOA for Lincosamide?

A

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis

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8
Q

What drug is a Lincosamide?

A

Clindamycin {Cleocin]

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9
Q

What is the MOA for Oxazolidinone?

A

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis –unique binding site results in no cross-resistance with other ribosomal ABX

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10
Q

What drug is a oxazolidinone?

A

Linezolid [Zyvox]

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11
Q

What is the MOA for Aminoglycosides?

A

Irreversibly inhibits ribosomal protein synthesis

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12
Q

What drugs are Aminoglycosides?

A

Gentamicin [Gentasol],

& Tobramycin [Tobrex]

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13
Q

Tetracycline

A

Tetracycline.

It interferes with bacterial 30S ribosome protein production

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14
Q

Doxycycline

[Vibramycin]

A

Tetracycline.

Interferes with bacterial 30S ribosome protein production

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15
Q

Erythromycin

[E.E.S.]

A

Macrolide.

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis

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16
Q

Clarithromycin

[Biaxin]

A

Macrolide.

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis

17
Q

Azithromycin

[Zithromax]

A

Macrolide.

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis

18
Q

Telithromycin

[Keteck]

A

Ketolide.

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis

19
Q

Clindamycin

[Cleocin]

A

Lincosamide.

Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis

20
Q

Linezolid

[Zyvox]

A

Oxazolidinone.
Reversibly bind to 50S subunit of bacterial ribosome and inhibit protein synthesis –unique binding site results in no cross-resistance with other ribosomal ABX

21
Q

Gentamicin

[Gentasol]

A

Aminoglycoside.

Irreversibly inhibits ribosomal protein synthesis

22
Q

Tobramycin

[Tobrex]

A

Aminoglycoside.

Irreversibly inhibits ribosomal protein synthesis

Antibiotics (3 decks)

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