Biochemistry- Nucleic Acids Flashcards

1
Q

What are the 2 pyrimidines found in DNA?

A

cytosine and thymine

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2
Q

What are the 2 pyrimidines found in RNA?

A

uracil and cytosine

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3
Q

What are the 2 purines found in RNA and DNA?

A

adenine and guanine

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4
Q

Uric acid is the breakdown product of what substance?

A

Purine catabolism

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5
Q

in DNA what are the 2 base pair combinations?

A

A-T, C-G

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6
Q

Making RNA from DNA template is known as what?

A

transcription

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7
Q

What are the 3 characteristic components of a nucleotide?

A

nitrogenous base, pentose sugar, phosphate group

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8
Q

In de novo synthesis of purines, what is the starting material?

A

Ribose-5-phosphate

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9
Q

Where does ribose-5-phosphate come from?

A

Hexose monophosphate shunt pathway

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10
Q

A nuceotide minus the phosphate group is known as what?

A

nucleoside

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11
Q

What is an important co-enzyme in purine and pyrimidine synthesis?

A

folic acid

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12
Q

What is the name for the last enzyme in the production uric acid from purines?

A

Xanthine oxidase

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13
Q

What are the precursors for pyrimidine synthesis?

A

Glutamine, CO2

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14
Q

Where does pyrimidine and purine catabolism mainly occur?

A

liver

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15
Q

Three consecutive base pairs are known as what?

A

codon

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16
Q

what is the function of transfer RNA?

A

bring the correct amino acid in line with the correct codon during translation