Rhonda Patrick

Question 1

How many replication errors occur due to the imperfection of DNA/RNA polymerases per cell division?

Answer 1

120,000 sequence errors per replication

99% of the errors are corrected by the polymerases

Question 2

Why is colon cancer more common than Duodenum cancer?

Answer 2

More cell divisions there. Colon 10x more divisions per lifetime.

Question 3

What is magnesium so important?

Answer 3

it affects the efficiency of DNA polymerase enzymes. (error and repair)

Eat chlorophyll containing leafy greens.

Question 4

What is the suprachiasmatic nucleus?

Answer 4

Master clock that influences circadian rhythms.

Question 5

What does melatonin do?

Answer 5

Shuts down/(and initiates?) certain metabolic activities

Question 6

What occurs among people that make more melatonin (like blind people)?

Answer 6

Less cancer

Question 7

What is Beta Amyloid

Answer 7

Potentially harmful protein involved in Alzheimer’s

Question 8

What is the importance of the medial prefrontal cortex?

Answer 8

It generates slow wave sleep that helps clears out amyloid beta. (a feedback loop begins in which more amyloid beta impairs slow wave sleep.)