PCOS Flashcards
1
Q
clinical features
A
menstrual irregularities hirsutism obesity subfertility recurrent miscarriage acanthosis nigricans elevated serum LH and insulin resistance
2
Q
dx
A
must have 2/3
- amenorrhea/oligoneborrhea
- clinical or biochemical hyperandrogenism
- polycystic ovaries on u/s
3
Q
mx of PCOS
A
COCP cyclical oral progesterone metformin clomiphene:induce ovulation for subfertility lifestyle advice weight reduction
4
Q
hirsutism
A
eflornithine cream applied topically
cyproterone acetate (anti-androgen contraceptive pills)
metformin
GnRH analogues with low-dose HRT:this regime should be reserved for wome intolerant of other therapies
surgical tx:laser or electrolysis
5
Q
definition
A
syndrome of ovarian dysfx along with the cardinal features of hyperandrogenism and PCO morphology
