Gluconeogenesis Flashcards
1
Q
Gluconeogenesis Reaction
A
2 Pyruvate + 4 ATP + 2 GTP + 2NADH –> glucose + 4 ADP + 2 GDP + 2 NAD
2
Q
(some amino acids, lactate –>) pyruvate –> oxaloacetate
A
pyruvate carboxylase, use 1 ATP
3
Q
(some amino acids –>) oxaloacetate –> phosphenolpyruvate
A
PEP carboxykinase, use 1 GTP
4
Q
fructose 1,6-bisphosphate –> fructose 6-phosphate
A
fructose 1,6-bisphosphatase
5
Q
glucose 6-phosphate –> glucose
A
glucose 6-phosphatase
6
Q
pyruvate carboxylase inhibition
A
insulin
7
Q
PEP carboxykinase inhibition
A
insulin, AMP
8
Q
PEP carboxykinase stimulation
A
glucagon, cAMP
9
Q
fructose 1,6-bisphosphatase inhibition
A
fructose 2,6-bisphosphate, AMP
10
Q
fructose 1,6-bisphosphatase stimulation
A
citrate, main regulation step
11
Q
glucose 6-phosphatase inhibition
A
insulin
12
Q
glucose 6-phosphatase stimulation
A
glucagon
