Pain

Question 1

anesthesia

Answer 1

absence of sensation, especially sensitive to pain

Question 2

analgesia

Answer 2

decreased or absent sensation of pain

Question 3

hyperalgesia

Answer 3

extreme sensitivity to pain

Question 4

hyperesthesia

Answer 4

extreme sensitivity of one of the body’s sense organs, like pain or touch

Question 5

allodynia

Answer 5

experience of pain from non-painful stimuli, like from light touch

Question 6

dysesthesia

Answer 6

abnormal, usually unpleasant sensation to touch

Question 7

hyperpathia

Answer 7

hypersensitivity to sensory stimuli, includes hyperesthesia, allodynia, and hyperalgesia

Question 8

WHO 3-step pain ladder

Answer 8

1= mild ASA acetaminophen, nsaids
2= moderate codeine, hydrocodone, oxycodone
3= severe morphine, hydromorphone...

Question 9

neuropathic

Answer 9

pain without a painful stimuli

Question 10

complex regional pain syndromes

Answer 10

pain due t o peripheral nerve fiber injury but with uncertain pathophysiology, etc, phantom limb pain

Question 11

neuralgias

Answer 11

nerve pain

Question 12

radicular

Answer 12

pain radiating to the lower like due to compression injury or inflammation of a spinal nerve root, (herniated disk)

Question 13

nociceptive

Answer 13

related to tissue injury/damage

Question 14

idiopathic

Answer 14

unknown origin or cause

Question 15

psychogenic

Answer 15

somatization disorders or hysterical reactions

Question 16

acetaminophen (tylenol)

peripheral agent

Answer 16

inhibits prostaglandin synthesis in the CNS

• has antipyretic and analgesic properties
• little anti-Inflammatory

Question 17

opiods

Answer 17

mimics actions of endogenous opiod peptides by interacting with opioid receptors (mu,delta, kappa)
-inhibits neurotranmitter firing = no pain

Question 18

bisphosphonates

Answer 18

some pain relief for bone metastases by decreasing osteclast activity and formation

Question 19

neuropathic agents

Answer 19

local anesthetics block transmission of pain signals from PNS to CNS

Question 20

anticonvulsant agents

Answer 20

inhibit Na+ and Ca+ voltage gated channels, decrease nerve firing
Gabapentin is used often

Question 21

NSAIDS

peripheral agent

Answer 21

Aspirin, ibuprofen, naproxen

inhibits synthesis of prostaglandins by inhibiting the COX enzyme