Pathophysiology Flashcards
What can be done to alleviate dry eyes?
plug in punctum, tears stay in eye longer, alleviate sx
What side of the eye is the worst to get a laceration on? Why?
medial side, because of superior and inferior canaliculi
can cut through and ruin drainage system
What does “injection” mean?
term used to describe the fine blood vessels that cause the conjunctiva to look pink or red
What are the common causes of intracranial hypertension?
- brain tumor
- venous sinus thrombosis
- meningitis
- hydrocephalus
- pseudotumor cerebri
- steroid withdrawal
- tetracycline therapy
What is the most commonly affected muscle in graves ophthalmopathy and what does this affect?
inferior rectus
restricts upward-gaze
results in vertical diplopia
What are the s and s of graves ophthalmopathy?
signs: proptosis periorbital edema symptoms: excessive tearing, conjunctivitis, eye or rtetroorbital pain blurred vision, dipolplia
What is the pathogenesis of Graves ophthalmopathy?
T lymphocytes activated, results in inflammation and infiltration of the orbital connective tissue
inflammation results in more deposits of collage and glycosaminoglycans in the muscles, which then swell and grow and push eye out of socket
What are the complications of graves ophthopathy?
- dry eyes, corneal ulcerations (from proptosis)
- EOM (diplopia, inability to look up, inability to converge)
what is proptosis?
forward perfusion of the globe with respect to the orbit
What is the treatment for Graves opthalmopathy?
- treat underlying hyperthyroidism
- mild sx (dark glasses, eye drops, raise head of bed)
- severe sx (glucocorticoids and if vision is threatened, radiation and then surgery)
What happens with Myasthenia Gravis (MG)?
ACh is gone, muscles don’t contract, get weakness, resulting in ptosis and binocular diplopia
can treat with anti cholinesterase meds (increasing the ACh available so there are less symptoms)
chronic or rapid immunomodulating to treat the AI
surgical (can remove thymus)
What are the red flags in ophthalmology?
- reduction of visual acuity
- severe deep pain (not irritation)
- ciliary flush
- photophobia
- severe foreign body sensation the prevents pt from keeping eye open
- fixed pupil
- severe headache with nausea
What is a ciliary flush?
patter of injection in which redness is MOST PRONOUNCED in a ring at the limbus (the limbus is the transition zone between the cornea and the sclera)
What is a subconjunctival hemorrhage?
signs, symptoms and dx, tx
blood vessel burst from conjunctiva
signs: red in eye
symptoms: none
dx: no photophobia, no foreign body sensation, no discharge, no change in visual acuity
tx: none, will heal in 1-2 weeks
What is keratoconus?
signs, sx, dx, tx
a degenerative disorder that causes the cornea to thin and change shape into more cone shape rather than curve
signs and sx: distortion of vision, photophobia, trouble reading, driving
tx: corrective lenses, and in some cases, surgery (corneal transplant, etc)