Hepatitis C

Question 1

what is the classification of HCV?

Answer 1

flavivirus, hepacivirus

Question 2

which area has the highest prevalence of HCV?

Answer 2

Egypt

Question 3

what is the risk of HCV sexual transmission in someone who is HCV positive only, and in a monogamous relationship?

Answer 3

low

Question 4

what is the risk of HCV sexual transmission in someone who is HCV AND HIV positive, and in a monogamous relationship?

Answer 4

moderate-high

Question 5

what is the only liver disease that oscillates between normal and abnormal (ALT levels / liver enzymes)?

Answer 5

hepatitis C

Question 6

what is the 5 year survival for patients with hepatocellular carcinoma?

Answer 6

less than 5%

Question 7

what is the main factor associated with fibrosis in HCV?

Answer 7

alcohol use (more than 50 g per day)

Question 8

who should be screened for hepatitis C, with or without risk factors?

Answer 8

baby boomers (1940 - 1964)

Question 9

what is the first test for HCV testing?

Answer 9

HCV antibody test (ELISA)

Question 10

what is the most common HCV genotype in the US?

Answer 10

genotype 1

Question 11

what is the most important factor in HCV prognosis?

Answer 11

genotype

Question 12

what is the primary goal of HCV therapy?

Answer 12

eradicate HCV infection

Question 13

what is the difference between HCV and HIV treatment?

Answer 13

there is an end to HCV treatment

Question 14

what is the significance of pegylating therapeutic agents?

Answer 14

increases the time it spends in the body

Question 15

what is the best therapy for HCV? why?

Answer 15

harvoni

one pill a day 
no side effects 
no monitoring 
8-12 weeks therapy 
95-99% SVR