Drugs

Question 1

Amiodarone side effects

Answer 1

Bradycardia (ca2+ channel blocking activity affects AV node)
ILD
Thyroid
Cutaneous / corneal microdeposits
Hepatic / hypersensitive grey skin

Question 2

Adenosine

Answer 2

Tx SVT (after vagal stimulation)
Transient AV block which slows conduction through AV node
Tx WPW

Question 3

Atropine

Answer 3

Tx symptomatic bradycardia

Anti-cholinergic
Anti-SLUD

Inhibits ACh (works on cardiac smooth muscle & sweat glands) which is main NT at NMJ
(dec ACh =>>> botulism, tetenus, paralysis)

Question 4

Laxatives

Answer 4

Osmotic = lactulose
Stimulant = metoclopramide, erythromycin

Mixed O & S =

Bulk forming = senna

Question 5

Olanzopine

Answer 5

Newer antipsychotic
Balances out chemicals in brain & relieves the disturbing symptoms
Close monitoring checking levels in your blood
S.E.: weight gain, oedema, diabetes, sleepiness
Advice: inform other doctors you are on this medication, don’t have alcohol or stop suddenly, take tablet as prescribed

Question 6

Lithium

Answer 6

Mood stabiliser, helps to prevent moments when you feel very high and very low
Advice: take as prescribed, to avoid alcohol, inform other doctors you are on this medication (high levels of lithium can be very dangerous)
S.E.:
Lack of energy
Intentional tremor
Teratogenic
Hypothyroid
Insipidus
Urine excess
Metallic taste
Close monitoring, checking wbc/levels of lithium in blood, ecg, pregnancy etc
Seek medical advice if you feel particularly unwell

Question 7

S.E immunosuppressants

Answer 7

Derm: seborrhoeic keratoses
Metabolic: cushingoid features (steroids)
Infection: re-activation of TB, HSV, viral warts
Malignant: melanoma, BCC/SCC

Question 8

Bisphosphonates

Answer 8

Works by slowing bone loss and increasing bone density
Several options:
Oral - daily, weekly monthly
Take with a glass of water, sitting up, no food for 30 mins afterwards
IV infusion - 3 monthly, annually
S.E. Headaches, gi disturbance, osteonecrosis of jaw
Recommend keeping good oral health & seeing dentist
Take for 3-5 yrs, 6-12 months for benefit to be seen
CI pregnancy & breastfeeding