Bone and Joint Infections Flashcards

1
Q

What do you look for in a drug to treat osteomyelitis?

A
  • Good bioavailability

- Good bone penetration

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2
Q

Some possible treatments for osteomyelitis

A
  • Metronidazole
  • Ciprofloxacin
  • Clindamycin
  • Bactrim (TMP-SMX)
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3
Q

Which bones lack a true cortex?

A

Vertebrae

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4
Q

How are short and long bones formed?

A

Endochrondrial ossification

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5
Q

How are flat bones formed?

A

Intermembranous ossification

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6
Q

What supplies nutrients to the outer 1/3 of the bone?

A

Periosteum

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7
Q

Epiphysis

A
  • Contains growth (epiphyseal) plate
  • Thin cortex, dense trabecular
  • Site of many attachments
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8
Q

Metaphysis

A
  • Metabolically active
  • Thin cortex, dense trabecular
  • Tendon attachments
  • Shapes growth
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9
Q

Diaphysis

A
  • Thick cortex
  • Smaller diameter
  • Intermedullary canal
  • Tendon attachments
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10
Q

Common findings in septic arthritis

A
  • Inflammation
  • Range of motion
  • Rash
  • Tenosynovitis
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