Diabetes Type I - Michels

Question 1

What cells are responsible for destruction of B islet cells in T1 diabetes?

Answer 1

T lymphocytes and B lymphocytes (humoral autoantibodies)

Question 2

Definition of Latent Autoimmune Diabetes of Adulthood (LADA): (diagnostic criteria)

Answer 2

1. Age 30-70 years at diagnosis
2. At least 6 months of non-insulin requiring diabetes
3. The presence of diabetes associated autoantibodies

Question 3

T1D assx conditions (3):

Answer 3

Autoimmune thyroid disease
Celiac Disease
Addison’s disease

Question 4

T2D assx conditions (4):

Answer 4

Obesity
Lipid abnormalities
PCOS (polycystic ovary diease)
NAFLD (non-alcoholic fatty liver disease)