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Pharm U3 > Headaches > Flashcards

Headaches Flashcards

1
Q

Analgesic NSAIDs used for acute treatment of moderate migraines and acute treatment of tension headaches

A 
Aspirin
Acetaminophen
Naproxen
Indomethacin
Piroxicam
Diclofenac
Ibuprofen
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2
Q

Barbiturate used for the treatment of migraines

A

Butalbital

Use when more traditional therapies unavailable or contraindicated

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3
Q

Opioids used for the acute treatment of migraines –generally for patients who wake up with a headache

A

Codeine
Meperidine
Oxycodone
Butorphanol

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4
Q

Corticosteroids used for the acute treatment of migraines and prolonged heat syndromes, also a rescue treatment for cluster headaches

A

Prednisone

Dexamethasone

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5
Q

Acute treatment of migraines though vasoconstriction and 5HT agonist in trigeminovascular pathway

A

Ergotamine

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6
Q

What are the side effects of ergotamine

A 
Nausea
Dizziness
Paresthesia
Chest pain
Abdominal cramps
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7
Q

What is contraindicated with the use of ergotamine for the acute treatment of migraines

A 
Women planning pregnancy
Uncontrolled HTN
Sepsis
Renal or hepatic failure 
Vascular dz
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8
Q

Used for acute treatment of migraines with less likelihood of the development of rebound headache than ergotamine. Can also be used for acute treatment of cluster headaches and short-term prevention of cluster headaches

A

Dihydroergotamine–DHE

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9
Q

What is the mechanism of action of Dihydroergotamine

A

Vasoconstriction and mainly 5HT agonist in trigeminovascular pathway

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10
Q

Contraindicated with the use of dihydroergotamine

A 
Women planning pregnancy
Uncontrolled HTN
Sepsis
Renal or hepatic failure
Vascular dz
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11
Q

Selective 5Ht1b-d agonist used for acute treatment of migraines

A

Sumatriptan

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12
Q

What is the mechanism of action of sumatriptan

A

Selective 5HT1b-d agonist
Penetration of CNS–constriction of extra cerebral intracranial vessels
inhibition of trigeminovascular system

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13
Q

Besides the acute treatment of migraines, what else is sumatriptan used for

A

Effective for photo/phonophobia
N/V
Acute treatment of cluster headaches

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14
Q

What are the side effects of sumatriptan

A

Flushing
Tingling
Dizziness
Chest discomfort

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15
Q

Injection used for the preventive treatment of chronic migraine headaches

A

Onabotulinum toxin A

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16
Q

Tri-cyclic antidepressants used for migraine and tension headache prevention

A

Amitriptylin
Protriptyline
Nortriptylin

17
Q

SSRIs used for migraine and tension headache prevention

A

Fluoxetine
Paroxetine
Sertraline

18
Q

B-blockers used for migraine prevention

A

Propranolol and timolol–> FDA

Nadolol and atenolol

19
Q

Ca channel blocker used for migraine prevention and useful in prolonged or disabling aura, or complicated migraine syndromes. Can also be used for long-term prevention of cluster headaches

A

Verapamil

20
Q

Anti epileptics used for migraine prevention

A

Valproic acid

Topiramate

21
Q

Acute treatment of cluster headaches–rebound can occur when stopped

A

O2

22
Q

Used for cluster headache prevention that is contraindicated with Na-depleting diuretics

A

Lithium

Pharm U3 (11 decks)

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