Autonomic Receptors Flashcards
increases vascular smooth muscle contraction
increases pupillary dilator muscle contraction (mydriasis)
increases intestinal and bladder sphincter muscle contraction
Receptor and G-Protein class
α1
q
decreases sympathetic outflow
decreases insulin release
decreases lipolysis
increases platelet aggregation
decreases aqueous humor production
Receptor and G-Protein class
α2
i
increases heart rate
increases contractility
increases renin release
increases lipolysis
β1
s
Vasodilation
bronchodilation
increases lipolysis,
increases insulin release
decreases uterine tone
(tocolysis)
ciliary muscle relaxation
increases aqueous humor production
β2
s
CNS, enteric nervous system
M1
q
decreases heart rate and contractility of atria
M2
i
increases exocrine gland secretions (e.g., lacrimal, salivary, gastric acid)
increases gut peristalsis
increases bladder contraction
bronchoconstriction
increases pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accommodation)
M3
q
α1
q
increases vascular smooth muscle contraction
increases pupillary dilator muscle contraction (mydriasis)
increases intestinal and bladder sphincter muscle contraction
α2
i
decreases sympathetic outflow
decreases insulin release
decreases lipolysis
increases platelet aggregation
decreases aqueous humor production
β1
s
increases heart rate
increases contractility
increases renin release
increases lipolysis
β2
s
Vasodilation
bronchodilation
increases lipolysis,
increases insulin release
decreases uterine tone
(tocolysis)
ciliary muscle relaxation
increases aqueous humor production
M1
q
CNS, enteric nervous system
M2
i
decreases heart rate and contractility of atria
M3
q
increases exocrine gland secretions (e.g., lacrimal, salivary, gastric acid)
increases gut peristalsis
increases bladder contraction
bronchoconstriction
increases pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accommodation)
