Nutrition, Body Weight And Homeostasis Flashcards

1
Q

Units of energy

A
  • kilojoule (kJ)
  • an everyday calorie is actually a kilocalorie (1000 calories = 1kcal)
  • 1kcal = 4.2kJ
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2
Q

Carbohydrates

17kJ.g / 4Kcal.g

A
Starch - polymer of glucose (can be digested by humans unlike cellulose) 
Sucrose - glucose-fructose disaccharide 
Lactose - galactose-glucose disaccharide
Fructose - monosaccharide 
Glucose - main sugar in human blood
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3
Q

Protein

16kJ.g / 4Kcal.g

A
  • amino acids joined to form linear chains
  • 20 different amino acids used for protein synthesis in the body
  • 9 essential amino acids cannot be synthesised by must be obtained from the diet
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4
Q

Energy

A
  • Biosynthetic Work - synthesis of cellular components
  • Transport Work - movement of ions & nutrients across membranes. brain cells use 50% of their energy on ion transport.
  • Mechanical Work - muscle contraction.
  • Electrical Work - nervous conduction.
  • Osmotic Work - kidney.
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5
Q

9 essential amino acids

A
If - Isoleucine 
Learned - Lysine 
This - Threonine 
Huge - Histidine 
List - Leucine 
May - Methionine 
Prove - Phenylalanine 
Truly - Tryptophan 
Valuable - Valine
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6
Q

Fat

37kJ.g / 9Kcal.g

A

Triacylglycerols - 3 fatty acids esterified
Contain much less oxygen that carbohydrates or protein - yield more energy when oxidised
Required for the absorption of the fat-soluble vitamins (ADEK) from the gut
Essential fatty acids needed for linoleic and linolenic acids

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7
Q

Minerals

A
  • electrolytes establish ion gradients across membranes and maintain water balance
  • calcium and phosphorus essential for structure (bones and teeth)
  • calcium is an important signalling molecule
  • enzyme co-factors (Fe, Mg, Mn, Co, Cu, Zn)
  • Fe is an essential component of Haemoglobin
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8
Q

Vitamins

A
  • essential for life
  • required in micro- or milligram quantities
  • fat or water soluble
  • deficiency diseases if inadequate intake (also possible to overdose)
    B12 - anaemia, B6 - dermatitis, C - scurvy
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9
Q

Dietary Fibre

A

Cellulose, Lignin, Pectins, Gums
- humans do not produce the enzymes required to break the beta-1,4 linkages in cellulose
- average requirement is 18g
- low fibre is associated. With constipation and bowel cancer
- high fibre reduces cholesterol and risk of diabetes
Liver makes bile salt from cholesterol, fibre absorbs this so it can not be reabsorbed so the liver has to make more bile salt

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10
Q

Dietary Reference Values

DRVs

A

Reference Nutrient Intake RNI - protein - enough to ensure that needs of 97.5%
Estimated Average Requirement EAR - used for energy - adequate for ~50% of the group (50% will need more)
Lower Reference Nutrient Intake - LRNI - enough for only a small number of people who have low requirements
- values depend on age, gender and levels of physical activity

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11
Q

Daily Energy Expenditure

A
- vary - age, sex, body composition and physical activity 
Is the sum of: 
Basal Metabolic Rate - BMR 
Diet-Induced Thermogenesis - DIT 
Physical Activity Level - PAL
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12
Q

BMR

A

Maintains the resting activity of the body
-biochemical reactions
- functions of organs
Affected by size, gender, environmental temperature, endocrine status, body temperature

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13
Q

Voluntary Physical Activity

A
  • energy required depends on intensity and duration

- reflects energy demands of skeletal, heart and respiratory muscle

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14
Q

Energy stores

A
  • muscles have a few seconds worth
  • carbohydrate stores for immediate use
  • long term stores of adipose ~ 40 days worth
  • muscle protein can be converted to carbohydrates under extreme conditions
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15
Q

Obesity

A

Excessive fat accumulation - adipose tissue
BMI > 30
Associated with an increase risk of developing some cancers, cardiovascular disease and type 2 diabetes

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16
Q

Body Mass Index

A

BMI = weight kg / (height m)^2

  • not accurate with muscular individuals
    Alternative measurement: waist/hip ratio
17
Q

Body fat distribution

A

greater proportion of fat in upper body (particularly in abdomen) compared with that on hips is associated with increased risk of:

  • insulin resistance
  • hyperinsulinism
  • type 2 diabetes
  • hyperlipidaemia
  • stroke
  • premature death
18
Q

Malnutrition

A

Marasmus - insufficient energy

Kwashiorkor - low protein

19
Q

Blood

A
Transport 
- supply of oxygen 
- supply of nutrients for utilisation, storage and inter-conversion 
- removal of waste products CO2, urea, lactic acid 
- signalling (e.g. Hormones) 
Coagulation 
Immune functions
Regulation of body pH 
Regulation of core body temperature 
Hydraulic functions
20
Q

Metabolite measurement in blood

A

Used as a snapshot to see what is going on metabolically

21
Q

Homeostasis

A

Homeostasis is not a steady state but a dynamic equilibrium.
Failure in homeostasis leads to disease.
RECEPTOR - sensing component
CONTROL CENTRE - sets the range
EFFECTORS - bring about the change
NEGATIVE FEEDBACK - corrects the deviation