Last Friday Path Flashcards

1
Q

bronchi vs bronchiole

A

bronchi have cartilage

bronchiole do not

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2
Q

bronchiectasis is what

Sx

A

permanent dilation of the bronchioles

chronic cough, very mucopirulent sputum production

assc with cystic fibrosis, airway obstruction in kids, tumor

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3
Q

disease where the alveoli dissolve and the air space in the lung is enlarged

A

emphysema - related to cigs

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4
Q

what cells aren’t making surfactant in a preme with respiratory distress syndrome

A

Type II pneumocyte

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5
Q

how do you measure the degree on pulmonary obstruction

A

Forced expiratory volume in one second

FEV1

usually do it as FEV1 / FVC (forced vital capacity)

if it’s less than like 70%, they it’s for sure an obstructive lung disease

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6
Q

if you give someone a bronchodilator and their FEV1 increases, what is going on>?

A

they have an obstructive pulmonary disease

so not emphysema, which is due to alveolar destruction

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7
Q

atelectasis

A

a complete or partial collapse of a lung or lobe of a lung

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8
Q

ARDS

A

acute respiratory distress syndrome

like preme RDS but in adults.

non cardiogenic pulmonary edema. microvascular and alveolar capillary injury due to things like sepsis, trauma, shock

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9
Q

transudate vs exudate

common examples to invade the plural space

A

transudate is mostly water - CHF

exudate has a buncha crud in it - parapneumonic/empyema, malignant neoplasm)

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10
Q

what labs do you see in B12/ folate deficient anemia

A

megaloblastic anemia

hypersegmented neutrophils

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11
Q

what lung infections can you get from bat guano

A

histoplasmosis

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12
Q

lung infections from rotting wood piles

A

blastomycosis

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13
Q

lung infection from sand in the southwest region

A

coccidiomycosis

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14
Q

barrel chest

what u thinking

A

emphysema

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15
Q

when

A

emphysema and chronic bronchitis

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16
Q

in asthmatics, what type of spore are you thinking of

A

aspergillus

17
Q

what causes destruction of the alveolar sac in emphysema

A

elastolytic proteinases degrade natural anti-proteinase protection which leads to a “progressive acinar destruction” (acinar is latin for berry)

18
Q

alpha 1 antitrypsin deficiency causes early onset

A

emphysema

all over the lungs, not just the top of bottom!

19
Q

in cig smoke emphysema what part of the lungs take the brunt of the destruction

A

upper lobes

20
Q

emphysematous patient develops accelrated SOB, what are you thinking

A

subpleural bleb rupture causing pneumothorax

21
Q

if you look at someone’s lung under the microscope who had lung problems and you don’t see any inflamation, what is it?

A

emphysema

22
Q

central acinar or common emphysema prefers what part of the lungs

A

upper

23
Q

pure bronchitics used to be called what

pure emphysematous patients were called what

A

blue bloaters

pink puffers (breathing shallow and frequently)

24
Q

primary ciliary dyskinesia

A

kartagener’s syndrome (missing the dynein arm in cillia)

also presents with sinus invertus

25
Q

if you see lobar pneumonia in an otherwise healthy person what are you thinking

A

pneumococcus (streptococcus pneumo)

26
Q

empyema

A

pleural space fills with pus