Ankylosing Spondylitis Flashcards

1
Q

What is ankylosing spondylitis?

A

Most common axial skeleton inflammatory disorder

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2
Q

What factor is associated with ankylosing spondylitis?

A

HLA-B27

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3
Q

What is the onset of ankylosing spondylitis?

A

Young adulthood

Sometimes in childhood
- Juvenile chronic polyarthritis

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4
Q

What are the s/s of ankylosing spondylitis?

A
Persistent LBP >3 months- in SI joint
Early morning stiffness
Relieved by exercise
Pain that wakes pt from sleep
Fatigue
Asymmetrical oligoarthritis 
Achilles tendinitis &/or heel pain
Extra-articular features
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5
Q

What is observed in PE in ankylosing spondylitis?

A
TTP
Spinal decreased ROM
Stooped posture (advanced)
Schober test
- Measures mobility of the lumbar spine
Chest expansion
- Thoracic spine
Peripheral joints
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6
Q

What are the labs used in ankylosing spondylitis?

A
RF
- Will be negative
ANA
- Will be negative
Sed rate
- Could be elevated
CRP
- Could be elevated
HLA-B27
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7
Q

What is imaging used in ankylosing spondylitis?

A

Plain films

  • Lumbar spine and SI joint
  • “Bamboo spine”

MRI
- Will show inflammatory changes before bony changes occur on plain films

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8
Q

What are the treatment options of ankylosing spondylitis?

A

Patient Education
Exercise
Medical Therapy

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9
Q

What are the medications used in treatment of ankylosing spondylitis?

A
NSAIDs
Corticosteroids
Sulfasalazine
Methotrexate
Other disease-modifying agents
Antibiotic therapy
Anti-TNF therapy
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