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Psychiatry > Pharm for Cognitive Function > Flashcards

Pharm for Cognitive Function Flashcards

ADHD, Cognitive Function

1
Q

focalin is what class of drug?

A

methylphenidate

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2
Q

daytrana is what class of drug?

A

methylphenidate

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3
Q

concerta is what class of drug?

A

methylphenidate

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4
Q

Dexedrine is what class of drug?

A

Amphetamine

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5
Q

vyvansevis what class of drug?

A

Amphetamine

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6
Q

atomoxetine class

A

non-stimulant , NRI

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7
Q

alpha 2 agonist mechanism

A

bind alpha receptors pre and post synaptically and cause more noradrenergic tone post synaptic

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8
Q

what is more sedating guanfacine or clonidine

A

clonidine b/c guanfacine is specific to alpha 2a receptors

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9
Q

Methylphenidate mechanism

A

blocks catecholamine reuptake

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10
Q

where is Lisdexamfetamine/Vyvanse metabolized

A

RBCs

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11
Q

Amphetamine action

A

increases release of catecholamines and blocks reuptake

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12
Q

atomoxetine mechanism

A

highly specific norepi reuptake inhibitor presynpaticallyie blocks transporter

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13
Q

what’s difference b/w stimulants and atomoxetine

A

non stimulants are locked onto transporters for long period of time

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14
Q

Venlafaxine mechanism

A

SNRI and seronergic at lower doses

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15
Q

Bupropion brandname

A

wellbutrin

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16
Q

bupropion mechanism

A

catecholamine reuptake inhibitor

17
Q

which tricyclics are sued

A

imipramine, desipramine, and nortriptyline

18
Q

alpha 2 agonist mechanism

A

bind alpha receptors pre and post synaptically and cause more noradrenergic tone post synaptic

19
Q

what is more sedating guanfacine or clonidine

A

clonidine b/c guanfacine is specific to alpha 2a receptors

20
Q

Donepezil bioavailability

A

100%

21
Q

Donepezil half life

A

50-70 hours

22
Q

Donepezil drug reactions

A

nausea, vomiting, (1st degree AV block and bradycardia are relative contraindication)

23
Q

Methylphenidate indication besides ADHD

A

improve attention after TbI

24
Q

dextroamphetamineindication besides ADHD

A

improve attention, memory impairment, cognition, depression,anergia,and impaired motivation following TBI

25
Q

duloxetine drug class

A

Sero- norepi uptake inhibitor

26
Q

Modafinil possible mechanism (4)

A

increase DA in NAcc
activate hypocretin (orexin) neurons in hypothalamus
decrease in GABA release
increase glutamate in thalamus

27
Q

Memantine mechanism/ drug class

A

NMDA receptor antagonist – decreases signal intesity

28
Q

Memantine BA

A

100%

29
Q

Memantine side effects

A

dizziness, nausea, and headache

Psychiatry (4 decks)

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