Gluconeogenesis Flashcards
What is needed for gluconeogenesis
Energy
Carbon source
Carnivores - AA
Herbivores - VFA
Where does it take place
Liver
Kidney
What does liver and kidney have needed for gluconeogenesis
G-6-phosphatase
Where is G-6Pase located
Membrane of ER
What causes release of G-6-P to the ER
Hydrolysis
How is G-6-P converted to glucose
G-6-phosphatase
What stimulates and inhibits G-6-Pase
Glucagon
Insulin
What are substrates
Lactate
Glucogenic AA - carnivores
VFA - propionate - herbivores
Glycerol
TCA Intermediates
What part of triglyceride can be substrate
Glycerol converted to DHAP
Why can FA not be substrate
Losses CO2 in TCA cycle not enough carbons
What shows that glycolysis is not the reverse of gluconeogenesis
Gluconeogenesis
= needs 4 ATP and 2 GDP
= 6 P bonds
Glycolysis is only 4
Glycogen stimulates
Gluconeogenesis
And gluconeolysis = glycogen to glucose
Yes
What source is gluconeogenesis from
Non CHO source
