L15 Circulation- Systemic Circulation I Flashcards

1
Q

Define pulse pressure.

A

Systolic- diastolic

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2
Q

Explain how elastin functions as a structural component of the vascular wall.

A

Arteries have internal and external elastic lamina, which distinguishes it from veins
-Elastic lamina is very elastic, gives arteries compliance

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3
Q

Explain how smooth muscle functions as a structural component of the vascular wall.

A

Arteries- very thick and powerful, found in tunica media

Veins- not as strong

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4
Q

Explain how collagen functions as a structural component of the vascular wall.

A

Arteries- less, found in tunia adventitia

Veins- lots of connective tissue, well developed system

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5
Q

Define compliance.

A

1

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6
Q

Explain how vessel wall compliance affects arterial pressure.

A

Increasing V of blood, increases pressure, which decreases compliance

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7
Q

Explain windkessel (hydraulic filtering) properties of the aorta.

A

1

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8
Q

Define the relationship between velocity, flow and vessel cross sectional area.

A

1

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9
Q

Define the functional importance of wall/lumen diameter ratio to regulation of arterial pressure.

A

Higher wall thickness/lumen diameter = greater control of vessel diameter and blood flow

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10
Q

Define pressure pulse.

A

1

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11
Q

Define mean arterial pressure.

A

Diastolic pressure + 1/3 pulse pressure

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12
Q

What happens to pulse pressure as vessels get further from the heart?

A

Pulse pressure widens (systolic P increases and diastolic P decreases)

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13
Q

Do mean arterial pressure incline or decline throughout the circulatory system?

A

Continuously declines

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14
Q

What is the primary factor in determining mean arterial pressure?

A

Diastolic pressure

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15
Q

What is the pulse pressure in capillaries and veins?

A

No pulse pressure b/c of all the organs being diffused

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16
Q

Where is the greatest decrease in arterial pressure?

A

Across the arterioles

17
Q

What are the compliance properties of elastic lamina, smooth muscle and collagen?

A

Elastic lamina has highest compliance, then smooth muscle, and collagen has lowest compliance

18
Q

What are the structural features of continuous capillaries?

A
  • Continuous endothelial cells
  • No fenestrations in wall
  • Tight jxns between cells
  • Continuous basal lamina
  • Found in muscle, connective tissue
19
Q

What are the structural features of fenestrated capillaries?

A
  • Continuous endothelial cells
  • Fenestrations w/ and w/o diaphragms
  • Continuous basal lamina
  • Found in kidney and intestine
20
Q

What are the structural features of discontinuous (sinusoidal) capillaries?

A
  • Discontinuous endothelial cells separated by wide spaces
  • Discontinuous basal lamina
  • Found in liver, bone marrow, spleen