NVD meds

Question 1

diphenoylxate (anticholinergic) w atropine (antidiarheal)

Answer 1

diphenoylxate (anticholinergic) w atropine (antidiarheal)
MOA: Used for anti- diarrheal synthetic opiate
acts on smooth muscle of intestines, inhibiting GI.
AE: burred vision, constipation, dizziness
Preg category C: risks cant be ruled out.

Question 2

Ondanestron

Answer 2

Antiemetic. Decreases nausea and vomiting.
MOA: unlcear but is a serotonin blocker that blocks actions of chemicals in body that induce nausea and vomiting.
Used for chemo N and V. and post op surgery nausea.
Preg Category B : can use if benefits outweigh risks.

Question 3

dimenhydrinate

Answer 3

Antiemetic
Histamine 1 antagonist.
Used to treat N and V caused by motion sickness. Blocks chemo receptor zone.
Preg Category B: can use if benefits outweigh risks.

Question 4

scopolamine

Answer 4

Antiemetic, anticholinergic transdermal patch.
used for motion sickness, N and V due to opiods and anaesthesia, pre-op to decrease saliva and resp secretions, spasms, and excessive GI motility (IBS and diverticulitits)
MOA: corrects neurotransmitter imbalances in CNS.
AE: blurred vision and drowsiness
Preg Cateogry C: risk cannot be ruled out

Question 5

Procholorperazine

Answer 5

Antiemetic, Antipsychotic.
MOA: neuroleptic drug used to tx nausea and vomiting and schizophrenia. Depresses CTZ in CNS.
Preg category C: risk cannot be ruled out.
Contraindicated in children under 2 years.

Question 6

Metoclopramide

Answer 6

Antiemetic-decreases nausea and vomiting
MOA: blocks dopamine in CTZ of CNS. Increases muscle contractions in the upper digestive tract. Speeds the rate at which stomach empties into the intestine. Often used for chemo induced emesis, GERD,
Preg category B