important monoclonal antibodies

Question 1

rituximab

Answer 1

anti-CD20 used in non-Hodgkin lymphoma

Question 2

ibritumomab

Answer 2

anti-CD20 used in non-Hodgkin lymphoma

Question 3

tositumomab

Answer 3

anti-CD20 used in non-Hodgkin lymphoma

Question 4

trastuzumab

Answer 4

anti-Her2 receptor used in breast cancer

Question 5

gemtuzumab

Answer 5

anti-CD33 used in AML

Question 6

alemtuzumab

Answer 6

anti-CD52 used in CLL

Question 7

cetuximab

Answer 7

anti-EGFR used in colon cancer

Question 8

panitumumab

Answer 8

anti-EGFR used in colon cancer

Question 9

bevacizumab

Answer 9

anti-VEGF used in colon cancer and age-related macular degeneration/ retinopathy

Question 10

ranibizumab

Answer 10

anti-VEGF-A used in age-related macular degeneration/ retinopathy

Question 11

tocilizumab

Answer 11

anti-IL-6-R used in RA and giant cell arteritis

Question 12

abciximab

Answer 12

anti-GP2b/3a receptor used for anticoagulation

Question 13

natalizumab

Answer 13

anti-integrin used in multiple sclerosis and Crohn’s dz

Question 14

omalizumab

Answer 14

anti-free IgE used in asthma

Question 15

denosumab

Answer 15

anti-RANKL used in osteoporosis

Question 16

palivizumab

Answer 16

anti-fusion protein preventing RSV attachment to host