Chapter 21 Flashcards
3 processes of cell development
cell division
morphogenesis
cell differentiation
genomic equivalence
all cells have the same DNA, so they have the same genes
how do we have different types of cells if all cells have genomic equivalence?
gene expression
differences arise during development by regulatory mechanisms
what does it mean to express a gene?
gene is expressed through a physical trait
differential gene expression
different cells have different genes that are active
heart cells and eye cells have same DNA, but different genes are expressed to give the cells different function
totipotent cell
a cell that can generate a completely new organism
cloning
using one or more somatic cells from a multicellular organism
makes a genetically identical individual
nuclear transportation
nucleus of an unfertilized egg cell or zygote is replaced from a nucleus from a differentiated cell
nuclear transportation creates fully developed creatures when…
nuclear transportation is from a nucleus of a less differentiated cell instead of a fully developed cell
process of cloning mammals
- mammary cell from donor taken, egg cell from donor taken
- nucleus removed from egg cell, mammary cells are cultured to cause differentiation
- cells fused
- grown in culture
- implanted in uterus of a different sheep
- clone is identical to mammary cell donor
x-inactivation
creates a random phenotype in offspring, even if a clone is genetically identical to the mother
stem cell
relatively unspecialized cell that can reproduce itself indefinitely and differentiate into specialized cells of any type
why are embryonic stem cells so controversial?
separated at the blastocyst stage
totipotent
taken from an unconsenting fetus
why are adult stem cells not as useful as embryonic stem cells?
they are pluripotent
transcriptional regulation of gene expression
cell determination- precedes differentiation
involves expression of genes for tissue-specific proteins