Riggs; Combined bio and CBT

Question 1

Aim

Answer 1

To evaluate the effect of fluoxetine vs. placebo in combination with CBT, on depression, substance abuse disorder and conduct disorder

Question 2

Method

Answer 2

IMD

randomised controlled study

Also had diagnosed conduct disorder and substance disorder

Question 3

Procedure

Answer 3

Ps spent 16 weeks being treated:
- Fluoxetine and a course of CBT directed at dealing with substance abuse

or

• Placebo and a course of CBT directed at substance abuse

Question 4

Results

Answer 4

Combination of fluoxetine and CBT may be the most effective option as it led to significant improvement on one measure of depression in comparison with CBT and placebo

Question 5

What was concluded

Answer 5

Fluoxetine and CBT had greater efficiency that the placebo did.

Results showed = fluoxetine combined with CBT may have simm safety and eff for depression in ps with active SUD.??