Chapter 57 Flashcards
1
Q
what is ulcerative colitis?
A
chronic inflammation of the mucosal lining of colon or rectum
2
Q
drugs classes for UC?
A
aminosalicylates
glucocorticoids
antidiarrheals
immunomodulators
3
Q
What do aminosalicylates do?
A
inhibits prostaglandins to decrease inflammation
4
Q
How long does it take for aminosalicylates to work??
A
2 to 5 weeks
5
Q
affects of long term use of glucocorticoids?
A
osteperosis, peptic ulcer disease, increased risk of infection
6
Q
adverse effects of antidiarrheals?
A
can cause teh colon to dilate and case toxic megacolon
7
Q
why would you take immunomodulators for UC?
A
Offer synergistic effect with steroids to create a synergistic effect to decrease inflammation
