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Molecular Biology > Cytoskeleton Proteins > Flashcards

Cytoskeleton Proteins Flashcards

1
Q

Binds subunits, prevents assembly. Is the opposite of profilin (actin subunits)

A

Thymosin

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2
Q

Binds subunits, speeds elongation (in actin subunits)

A

Profilin

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3
Q

Nucleated assembly to form a web and remains associated with minus end (actin subunits)

A

ARP complex

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4
Q

Binds ADP-actin filaments, accelerates disassembly (actin filaments)

A

Cofilin

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5
Q

Severs actin filaments and binds to plus end (causes stickiness between filaments, which leads to weaker cytoskeleton)

A

Gelsolin

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6
Q

Prevents assembly and disassembly at the plus end (actin filaments)

A

Capping protein

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7
Q

Stabilizes filament (prevents actin filament from interacting with other proteins)

A

Tropomyosin

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8
Q

Cross links actin filaments into loose bundles

A

Alpha actinin

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9
Q

Cross links actin filaments into tight bundles, excluding myosin II

A

Fimbrin

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10
Q

Helps to cross-link many tightly bundled actin filaments

A

Villin

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11
Q

Promotes formation of a loose and highly viscous-gel like network by clamping together 2 actin filaments at roughly right angles

A

Filamin

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12
Q

Binds subunits, prevents assembly (acts opposite of gamma-TURC) in microtubules

A

Staminin

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13
Q

Nucleated assembly and remains associated with minus ends (stabilizing) in microtubules

A

Gamma Turcs

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14
Q

Remains associated with growing plus end and can link them to other structures in microtubules

A

TIPs

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15
Q

Enhances catastrophic disassembly at plus end in microtubules

A

KINESIn 13

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16
Q

Severs microtubules

A

Katanin

17
Q

Stabilizes tubules by binding along sides (opposes KINESIn) in microtubules

A

MAPs

18
Q

Cause bundling of microtubules

A

MAP2 and Tau

19
Q

Cross linking protein, links microtubules to intermediate filaments

A

Plectin

20
Q

Involved in nucleation of microtubules growth

A

Gamma tubulin

21
Q

Nucleates assembly and remains associated with growing plus end in actin subunits

A

Formin

Molecular Biology (2 decks)

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